LabCorp Test

Adrenal 21-Hydroxylase Autoantibodies Blood Test (Endocrine Sciences)

Quick Overview

21-Hydroxylase antibodies are markers of autoimmune Addison disease, which may manifest alone or as part of type I or type II polyglandular autoimmune syndrome.

Test #500092

$149.00

Availability: In stock

Preparation No special preparation required.
Test Results 9-11 days. May take longer based on weather, holiday or lab delays.

21-Hydroxylase antibodies are markers of autoimmune Addison disease, which may manifest alone or as part of type I or type II polyglandular autoimmune syndrome. These antibodies may be present even before the endocrine function is reduced.

 Autoimmune adrenal disease is divided into stages. Initially, the adrenal glands may be enlarged and have extensive lymphocytic infiltration. With chronic disease, the glands can be small and sometimes difficult to locate. A thickened and fibrotic capsule is seen, and the cortex is completely destroyed, although some small clusters of adrenocortical cells surrounded by lymphocytes may exist, and the medulla is relatively spared. Adrenal insufficiency is clinically apparent only after 90% or more of the cortex has been destroyed.

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