Anemia Profile Blood Test, Megaloblastic

Anemia Profile Blood Test, Megaloblastic

Quick Overview

Profile for Megaloblastic Anemia that includes Cystathionine, homocysteine, 2-methylcitric acid, and methylmalonic acid.  Elevated levels of methylmalonic acid provide an early indication of cobalamin (B12) deficiency.

Test #706960

$400.00

Availability: In stock

Also Known As Megaloblastic Anemia
Preparation No special preparation required.
Test Results 7-9 days. May take longer based on weather, holiday or lab delays.

The megaloblastic anemia profile monitors four compounds: methylmalonic acid, 2-methylcitric acid, homocysteine, and cystathionine. It has been shown that all four of these compounds are elevated if a patient is suffering from vitamin B12deficiency (megaloblastic anemia, cobalamin deficiency) and that homocysteine and cystathionine are elevated if there is a folic acid deficiency. Methylmalonic acid and homocysteine are the primary tests for diagnosis. 2-Methylcitric acid and cystathionine provide confirmatory information.

This method is a more specific diagnostic tool for B12 and folate deficiencies as it has been shown that some patients with deficiencies will have normal or borderline serum B12 or folate. A deficiency of vitamin B12 can lead to incapacitating and life-threatening neuropsychiatric abnormalities, which are completely reversible by treatment with B12. As with any such condition early detection is very important. This profile provides early detection and differentiation. This differentiation is very important because both B12 and folate deficiencies have indistinguishable hematological abnormalities. The greatest improvement is observed when the proper vitamin is used and only B12 will correct the neuropsychiatric abnormalities seen in cobalamin deficiency.

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