Aldosterone:Renin Ratio Blood Test

Aldosterone:Renin Ratio Blood Test

Quick Overview

Test includes Aldosterone, plasma renin activity (PRA).

Test #004354


Availability: In stock

Preparation No fasting required. If possible, medications should be stopped 4 weeks prior to collection. Check with physician before stopping any medications. Collection should be performed mid morning, after the patient has been up (sitting, standing, or walking) for at least two hours and seated for 5 to 15 minutes prior to draw.
Test Type Blood
Test Results 5-7 days. May take longer based on weather, holiday or lab delays.

Patient Preparation:  Patients should be instructed to maintain an unrestricted dietary salt intake prior to testing. Washout of all interfering antihypertensive medications may be considered in patients with mild hypertension, but is potentially problematic in others and perhaps unnecessary in that medications with minimal effect on the ARR can be used in their place. The patient should not take drugs that markedly affect the ARR for at least four weeks prior to blood collection. These drugs include: Spironolactone, eplerenone, amiloride, and triamterene; Potassium-wasting diuretics; and products derived from liquorice root (eg, confectionary licorice, chewing tobacco).

Aldosterone is a mineral (salt)-retaining steroid and a hormone that directly regulates the retention of sodium (salt) by the kidneys and indirectly regulates the excretion of potassium. It is vital in the control of blood volume and blood pressure. Aldosterone is produced by the adrenal cortex, which is the outer portion of the two adrenal glands that are located at the top of each kidney. In most cases it is necessary to measure both renin and Aldosterone (and occasionally cortisol) in order to get a complete picture of what is happening with hormone production. These tests may be ordered to help in diagnosing and monitoring conditions associated with Aldosterone excess or deficiency.

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