LabCorp Test

Anemia Profile Blood Test, Megaloblastic

Quick Overview

The megaloblastic anemia profile blood test includes testing the levels of cystathionine, homocysteine, 2-methylcitric acid, and methylmalonic acid in the blood.

Test #706960

$469.00

Availability: In stock

Also Known As Megaloblastic Anemia; cobalamin deficiency; vitamin B-12 deficiency anemia; folate deficiency anemia; macrocytic anemia
Preparation No special preparation required.
Test Results 7-9 days. May take longer based on weather, holiday or lab delays.

The megaloblastic anemia profile monitors four compounds, cystathionine, homocysteine, 2-methylcitric acid, and methylmalonic acid, which will allow for a diagnosis of megaloblastic anemia to be determined. It has been established that each one of the four compound levels is higher than normal when an individual is affected by megaloblastic anemia. Methylmalonic acid and homocysteine are critical tests to make a diagnosis. 2-Methylcitric acid and cystathionine give corroborating information. 

This method is a more specific diagnostic tool for B12 and folate deficiencies as some patients with deficiencies have been shown to have normal or borderline B12 serum or folate. A vitamin B12 deficiency may result in disabling and life-threatening neuropsychiatric defects that are reversible through B12 therapy. Early detection is essential as with any such disease. This profile makes it possible for early detection and differentiation. This differentiation is very crucial due to the same hematological defects of both B12 and folate deficiencies. The most significant improvement is seen when the appropriate vitamin is used, and only B12 will correct the cobalamin deficiency neuropsychiatric abnormalities. 

Megaloblastic anemia is a form of anemia, a blood disorder indicated by a decreased amount of red blood cells. Red blood cells carry oxygen throughout the body. If the body doesn't have enough red blood cells, it doesn't get enough oxygen for the tissues and organs. 

There is a multitude of types of anemia, each with distinct causes and compositions. Megaloblastic anemia is symbolized by red blood cells being bigger than what is considered normal, and there is not a sufficient amount of them. 

Megaloblastic anemia is the result of improper production of red blood cells. Due to the cells being too big, they are not able to enter the bloodstream and generate oxygen from the bone marrow.

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