Angiotensin Converting Enzyme (ACE) Blood Test

Angiotensin Converting Enzyme (ACE) Blood Test

Quick Overview

This test is useful in evaluating patients presenting with sarcoidosis, Gaucher's disease and lymphoangiomyomatosis in that the enzyme is increased in these clinical settings.

Test #683


Availability: In stock

Also Known As Serum Angiotensin Converting Enzyme; SACE

No special preparation required.

Test Results 3-5 days. May take longer based on weather, holiday or lab delays.

Doctors most often use the ACE level test to monitor a disease called sarcoidosis. This condition causes inflammatory cells called granulomas to form in the body, leading to organ inflammation. Organs that may be affected by sarcoidosis include the:

  • lungs
  • skin
  • eyes
  • lymph nodes
  • liver
  • heart
  • spleen

People with sarcoidosis may experience fatigue, fever, and unexplained weight loss. Other symptoms include:

  • night sweats
  • a loss of appetite
  • swollen lymph nodes
  • joint pain
  • dry mouth
  • nosebleeds

The granulomas associated with sarcoidosis increase the amount of ACE in the blood. A doctor may use the ACE level test to help confirm a sarcoidosis diagnosis or to monitor treatment for sarcoidosis.

Your doctor may also use the ACE level test to assess the effectiveness of treatments for other medical conditions. One condition that may be monitored with an ACE level test is Gaucher’s disease. This is an inherited condition that causes fatty substances called lipids to build up in cells and internal organs. Symptoms include easy bruising, fatigue, and bone pain. High levels of the ACE enzyme can suggest you have Gaucher’s disease and can also be used to track response to medical therapy.

Other conditions that may cause lower-than-normal ACE levels include:

  • chronic obstructive pulmonary disease (COPD)
  • hypothyroidism
  • cystic fibrosis
  • emphysema

Conditions that may cause higher-than-normal levels of ACE include:

  • cirrhosis
  • Gaucher’s disease
  • psoriasis
  • amyloidosis
  • diabetes
  • HIV
  • histoplasmosis
  • hyperthyroidism
  • leprosy
  • lymphoma
  • tuberculosis

While an ACE level test can help reveal signs of underlying medical conditions, the test is rarely used to diagnose these conditions. Other tests are usually done along with an ACE level test before a diagnosis is confirmed.

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