Quest Test

Bilirubin Direct Blood Test

Quick Overview

Evaluate liver and biliary disease. Increased direct bilirubin occurs with biliary diseases, including both intrahepatic and extrahepatic lesions.

Test #285


Availability: In stock

Also Known As Bilirubin, Total, Conjugated, and Unconjugated
Preparation No special preparation required.
Test Results 7-8 days. May take longer based on weather, holiday or lab delays.

The bilirubin blood test measures the level of bilirubin in the blood. Bilirubin is typically a yellowish-brown color found in bile.  This fluid is produced by the liver when the liver breaks down old red blood cells.  Once it is produced, it is then discarded from the body through the stool. If bilirubin is not being attached to the glucose-derived acid (conjugated) in the liver or is not being removed from the bloodstream, this can be a sign that there is damage to the liver.

High bilirubin may be contributed to problems with the liver, gallbladder, or bile ducts. Some of those problems include:

  • liver diseases, like hepatitis
  • cancer of the gallbladder or pancreas
  • Gilbert’s syndrome, a genetic disease
  • gallstones
  • cirrhosis, which is scarring of the liver
  • drug toxicity
  • biliary stricture, where part of the bile duct is too narrow to allow fluid to pass

High bilirubin may also be contributed to problems in the blood instead of in the liver. Blood cells breaking down too fast can be caused by:

  • Hemolytic anemia
  • Transfusion reaction


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