Quest Test

Complement C3 Blood Test

Quick Overview

Used to determine whether deficiencies or abnormalities in the proteins that are part of the complement system are contributing to increased infections or increased autoimmune activity; and to monitor the activity of autoimmune diseases.

Test #351


Availability: In stock

Also Known As C3, C3 (β1C/β1A Globulin), C3 Complement
Preparation No special preparation required.
Test Results 2-3 days. May take longer based on weather, holiday or lab delays.

The complement system is a group of proteins that are important to protect you from infection and play a role in the development of inflammation.

There are nine major protein complements. They are labeled between C1 and C9. The complement C3 is the most important and abundant protein in the complement system. These various components pass through your bloodstream to find foreign invaders such as bacteria and viruses. When this happens, the complement system is activated and functions as a cascading event like the fall of a domino series. The results of complement activation are mostly favorable; the "foreign invader "is removed without damage to cells or tissues. However, in some people the activation of the complement system becomes uncontrolled, or some components may be deficient causing the risk of recurrent mild or serious bacterial infections or autoimmune disease. 

There are a number of conditions associated with lower than normal complement levels, such as increased bacterial infections, cirrhosis, rheumatoid arthritis, kidney disease, hepatitis, septicemia, and malnutrition. Increased levels of complement may be related to acute or chronic inflammation or thyroiditis, cancer, or ulcerative colitis.

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