Simply put, a D-dimer blood test detects or helps rule out the presence of blood clot. A blood clot is a clump of blood that is necessary to prevent you from losing too much blood when dealing with injuries. Scientifically, the D-dimer blood test measures the amount of protein called “fibrin D-dimer.” Fibrin D-dimer is produced whenever Fibrin, a protein that is a chief component of blood clot, is being actively degraded within the vascular system.