Understanding PIK3CA-Related Overgrowth Spectrum (PROS)

Understanding PIK3CA-Related Overgrowth Spectrum

PIK3CA-Related Overgrowth Spectrum (PROS) is a complex group of rare genetic disorders characterized by mutations in the PIK3CA gene, leading to diverse manifestations including overgrowth of body tissues, vascular malformations, and a range of specific conditions like CLOVES Syndrome and Megalencephaly-Capillary Malformation

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