LabCorp Test

Corticosteroid-Binding Globulin (CBG) Blood Test

Quick Overview

Corticosteroid-binding globulin (CBG, transcortin) is the main transport protein for cortisol and corticosterone in vertebrates. This protein binds glucocorticoids with high affinity. In some species, it also binds progesterone and to a lesser extent testosterone. Its specificity varies among species. CBG is important in regulating the actions of glucocorticoids.

Test #500130


Availability: In stock

Also Known As CBG, Corticosteroid-binding Globulin (CBG) Transcortin
Preparation No special preparation required.
Test Results 7-10 days. May take longer based on weather, holiday or lab delays.

Corticosteroid-binding globulin (CBG) is the specific high-affinity plasma transport glycoprotein for cortisol. Stress-induced falls in CBG levels may heighten hypothalamic–pituitary–adrenal axis responses and CBG:tissue interactions may allow targeted cortisol delivery. Three genetic variants of CBG have been identified that reduce cortisol binding affinity and/or CBG levels.

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