Aldosterone:Renin Ratio Blood Test

What is the purpose of this test?

The Aldosterone: Renin Ratio Blood Test is used to screen for primary aldosteronism, a condition where the adrenal glands produce too much aldosterone, a hormone that helps regulate blood pressure and sodium/potassium balance. This condition is a common cause of secondary hypertension (high blood pressure caused by another medical condition). The test measures the ratio of aldosterone to renin (a hormone released by the kidneys) to help determine whether the cause of high blood pressure is hormonal or related to other issues like kidney disease.

High levels of aldosterone with low levels of renin may indicate that the adrenal glands are producing excess aldosterone, possibly due to an adrenal tumor or overgrowth. Identifying this imbalance is crucial because primary aldosteronism may not respond well to standard high blood pressure treatments but can often be managed or even cured with the right therapy. This hormone blood test provides valuable information to help guide treatment decisions and prevent complications such as stroke, heart attack, or kidney damage.

Who should get this test?

The Aldosterone: Renin Ratio Blood Test may benefit individuals who:

• Have resistant or hard-to-control high blood pressure
• Have low potassium levels not explained by diet or medication
• Show signs of adrenal gland disorders
• Have a family history of early-onset hypertension or stroke
• Are under 40 and newly diagnosed with high blood pressure
• Have an adrenal mass or tumor seen on imaging scans
• Are being evaluated for the cause of secondary hypertension

When should I order the Aldosterone: Renin Ratio Blood Test?

Individuals may consider ordering this test if they have symptoms or health concerns that suggest an imbalance in aldosterone or renin levels.

Symptoms to consider:

• High blood pressure that doesn’t improve with standard medications
• Muscle weakness or spasms due to low potassium
• Frequent urination or thirst
• Fatigue or unexplained tiredness
• Headaches or dizziness
• Tingling or numbness in the hands or feet
• If you have these symptoms or suspect an adrenal hormone imbalance, the Aldosterone: Renin Ratio Blood Test can provide useful information to guide you and your doctor in managing your health and choosing the right treatment plan.