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Antipsychotic Drug Profile Blood Test

The Antipsychotic Drug Profile Blood Test detects the presence of antipsychotic drugs used to treat serious mental illnesses in a blood sample.

Test Code: 809569

CPT Code: 80344

Also Known As:


Liquid Chromatography/Tandem Mass Spectrometry (LC/MS-MS)

Specimen Type: Blood


No special preparation is required.

Test Results:

7-10 days. May take longer based on weather, holiday, or lab delays.


The Antipsychotic Drug Profile Blood Test screens for the following drugs:

  • Chlorpromazine | Clozapine
  • Fluphenazine
  • Haloperidol
  • Mesoridazine
  • Perphenazine | Prochlorperazine | Promazine | Promethazine
  • Thioridazine | Trifluoperazine


What is the purpose of this test?

If you are concerned about your mental health and have been prescribed antipsychotic medication, you may consider ordering the Antipsychotic Drug Profile Blood Test. This test detects the presence of antipsychotic drugs in your bloodstream, which can help ensure that you are taking the correct dosage and that the medication is being metabolized properly. Antipsychotic drugs are primarily used to treat serious mental illnesses related to psychosis, such as schizophrenia or bipolar disorder. However, it's important to note that these drugs can also treat other conditions, such as anxiety or depression. By monitoring the levels of antipsychotic drugs in your blood, your healthcare provider can make informed decisions about your treatment plan and ensure you receive the best possible care.


What conditions are treated by antipsychotic drugs?

Antipsychotics are medications used to treat conditions that involve or cause psychosis. Such conditions may include:


  • Schizophrenia
  • Bipolar disorder
  • Mania
  • Major depressive disorder accompanied by symptoms of psychosis
  • Delusional disorder
  • Severe agitation
  • Borderline personality disorder
  • Dementia
  • Delirium
  • Substance-induced psychotic disorder


Antipsychotics work by blocking or reducing the activity of certain chemicals in the brain that are associated with psychotic symptoms, such as hallucinations, delusions, and disordered thinking. It is important to note that antipsychotics should only be taken under the guidance and supervision of qualified healthcare providers, as they can have significant side effects and can interact with other medications.


When should I order an Antipsychotic Drug Profile Blood Test?

Individuals may order this test if they have experienced side effects related to the usage of antipsychotic drugs. Common side effects of antipsychotic drugs include:


  • Jaundice
  • Dizziness
  • Drowsiness
  • Weight gain
  • Dry mouth
  • Constipation
  • Urinary retention
  • High cholesterol (hyperlipidemia)
  • High blood sugar (hyperglycemia)
  • Heart and circulatory problems
  • Increased risk for developing Type 2 diabetes
  • Drug-induced movement disorders

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