Quick Facts
- Sample: Random urine sample
- Fasting: No special preparation is required
- Turnaround: 9-12 business days. May take longer due to weather, holiday, or lab delays.
What This Test Measures
This test measures urinary levels of 11-Dehydro Thromboxane B2 (11dhTxB2), a stable breakdown product of thromboxane A2 and a marker of platelet activation, using an enzyme-linked immunoassay (ELISA). The report also includes urine creatinine, which is directly measured, and the 11dhTxB2/creatinine ratio, which is a calculated value derived from these two measurements.
The sample is collected as a single, random urine specimen rather than a timed or fasting collection. Higher 11dhTxB2 levels may reflect increased platelet activation, while lower levels are consistent with reduced thromboxane production. This test evaluates thromboxane-related platelet activity; it does not independently diagnose cardiovascular disease or confirm how a specific individual will respond to therapy.
Benefits
- Measures 11dhTxB2, a urinary marker of platelet activation
- Uses a random urine sample, no blood draw required
- Reports urine creatinine and the 11dhTxB2/creatinine ratio
- Distinguishes directly measured results from calculated ratios
- Convenient collection compared to time-sensitive blood-based platelet tests
- Supports provider discussions about aspirin therapy
Who Is This Test For?
- Individuals currently taking aspirin therapy under medical guidance
- People whose provider wants to evaluate platelet activation status
- Patients being monitored for the biological effect of aspirin
- Individuals whose provider is assessing antiplatelet therapy effectiveness
- People whose provider wants an alternative to blood-based platelet testing
- Adults interested in urinary thromboxane biomarker testing
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. What does this test measure?
This test measures urinary 11-Dehydro Thromboxane B2 (11dhTxB2) using an ELISA method, a directly measured marker of thromboxane production and platelet activation. It also reports urine creatinine, which is directly measured, and the 11dhTxB2/creatinine ratio, which is calculated from these two results. The specimen is a single, random urine sample rather than a timed collection, and this test does not include other platelet function or cardiovascular biomarkers. These results may help a healthcare provider evaluate platelet activation and the biological effect of aspirin therapy. This is not a panel, and it does not independently diagnose cardiovascular or platelet-related conditions.
2. Who should consider this test?
People currently taking aspirin therapy, or those whose provider wants to evaluate platelet activation and the biological effect of aspirin, may consider this test. It may also be used to help monitor antiplatelet therapy. It is intended for use as directed by a healthcare provider, is not appropriate for every person with cardiovascular concerns, and results should be reviewed with your provider rather than used in place of a full medical evaluation.
3. Do I need to fast before this test?
No special preparation is required for this test.
4. How quickly will I get results?
Results are typically available in 9-12 business days. This may take longer based on weather, holiday, or lab delays.
5. How do I interpret the results?
The meaning of your 11dhTxB2, creatinine, and 11dhTxB2/creatinine results depends on your individual health history, medications, supplements, and the timing of your urine collection. Directly measured and calculated results should not be interpreted interchangeably. An elevated or reduced result does not, by itself, confirm or rule out a specific condition or therapy response.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
6. What should I do if my results are abnormal?
Review your results with a qualified healthcare provider, who can weigh them against your health history and other relevant factors. Do not start, stop, or change any medication based on this result alone. Your provider may consider additional evaluation or testing if clinically appropriate.
7. How often should I get tested?
Testing frequency should be determined as directed by your healthcare provider based on your individual situation and treatment plan. This test does not have a predefined routine testing schedule.
Pre-test preparation
No special preparation is required for this test. The specimen is collected as a single, random urine sample rather than a timed or fasting collection.
