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Cardio IQ® Lp-PLA2 Activity Blood Test

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The Cardio IQ® Lp-PLA2 Activity Blood Test measures the amount of Lp-PLA2 enzyme in the blood to evaluate an individual's risk factors for cardiovascular diseases.


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Test Code:


CPT Code(s):



Enzymatic Assay (EZA)




Fasting is preferred.

Test Results:

4-5 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI

What is the purpose of this test?

The Cardio IQ® Lp-PLA2 Activity Blood Test is a highly specialized diagnostic test used to measure the amount of Lp-PLA2 (lipoprotein-associated phospholipase A2) enzyme in the blood. Lp-PLA2 is an enzyme primarily produced by inflammatory cells in the body and is known to be associated with the development of atherosclerosis, a condition characterized by plaque buildup in the arteries.


The test is beneficial for patients who have a family history of heart disease or who have other risk factors such as high blood pressure, high cholesterol, or diabetes. By measuring the amount of Lp-PLA2 in the blood, the test can help healthcare providers assess the risk of cardiovascular disease and identify patients who may benefit from more aggressive treatment.


The results of this test can provide valuable information to healthcare providers about a patient's risk of heart disease and help them determine the most appropriate course of action. For example, suppose a patient has a high level of Lp-PLA2 in their blood. In that case, their healthcare provider may recommend lifestyle changes such as a healthy diet, exercise, smoking cessation, or medication to help lower their cholesterol and reduce their risk of heart disease.


Overall, the Cardio IQ® Lp-PLA2 Activity Blood Test is an important tool for doctors to assess a patient's risk of cardiovascular disease and develop an effective treatment plan. This test can help prevent serious health problems and improve patient outcomes by identifying patients at a higher risk of heart disease.


What factors increase the risk of cardiovascular diseases?

Several factors increase the risk of cardiovascular diseases. Some of the common ones include:


  • High blood pressure
  • High cholesterol levels
  • Smoking
  • Diabetes
  • Obesity
  • Family history of heart disease
  • Lack of physical activity
  • Age
  • Stress


Keeping these risk factors in check is important by making healthy lifestyle choices, such as eating a balanced diet, exercising regularly, not smoking, and managing stress effectively. Regular health checkups and consultations with a healthcare professional can help identify and manage these risk factors.


When should I order a Cardio IQ® Lp-PLA2 Activity Blood Test?

Individuals may order this test if they have experienced symptoms related to cardiovascular disease. Common signs or symptoms of cardiovascular disease include:


  • Chest pain or discomfort
  • Shortness of breath
  • Irregular heartbeat
  • Dizziness or lightheadedness
  • Fatigue
  • Swelling in the legs, ankles, or feet
  • Nausea or vomiting
  • Pain in the neck, jaw, or back


It's important to note that not everyone experiences the same symptoms of cardiovascular disease, and some people may not experience any symptoms at all. If you're concerned about your heart health, talking to your healthcare provider is always a good idea.

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