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Cortisol Awakening Response Saliva Add-On - Genova Test Kit

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The Cortisol Awakening Response Saliva Add-On - Genova Test Kit measures cortisol levels in saliva samples collected upon awakening and at subsequent intervals to assess adrenal function and the body's response to stress.


Test Code:






Shipping samples Monday - Thursday only is recommended to avoid shipment delays. Overnight fasting is required before collection. Patients should refrain from taking any medications or supplements until after collection. Consult with your physician prior to stopping any medications. Make sure to read and follow all collection instructions.

Test Results:

7-14 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.

The Cortisol Awakening Response Saliva - Genova Test Kit can be added to any of the following tests: 

  • Menopause Plus™ (GD4100)
  • Rhythm Plus™ (GD4102)
  • Male Hormones Plus™ (GD4105)
  • One Day Hormone Check™ (GD4106)
  • Adrenocortex Stress Profile™ (GD4300)


What is the purpose of this test?

The Cortisol Awakening Response Saliva Test Kit is designed to assess the cortisol awakening response (CAR), a natural physiological rhythm characterized by a sharp increase in cortisol levels within the first hour after waking. This test measures cortisol levels in saliva samples collected upon awakening and at subsequent intervals, providing insights into the body's stress response and adrenal gland function. The CAR is crucial for regulating energy, mood, and stress adaptation throughout the day, and abnormalities in this response have been linked to various health conditions, including adrenal dysfunction, chronic stress, fatigue, anxiety, and mood disorders. By evaluating the CAR, this test helps healthcare providers assess the integrity of the HPA (hypothalamic-pituitary-adrenal) axis and guide personalized interventions to optimize stress management, adrenal health, and overall well-being for individuals experiencing stress-related symptoms or adrenal fatigue.


The Cortisol Awakening Response Saliva - Genova Test Kit measures the following:

  • Cortisol Waking
  • Cortisol Morning - AM30
  • Cortisol Morning - AM60


Benefits of the Cortisol Awakening Response Saliva - Genova Test Kit:

  1. Assessment of Stress Response: It provides valuable insights into the body's cortisol awakening response (CAR), aiding in the evaluation of how the body responds to stress and its ability to regulate stress hormones.
  2. Identification of Adrenal Dysfunction: Abnormalities in the CAR can indicate potential dysfunction in the adrenal glands or the hypothalamic-pituitary-adrenal (HPA) axis, helping healthcare providers diagnose conditions such as adrenal fatigue, adrenal insufficiency, or HPA axis dysregulation.
  3. Personalized Stress Management: By understanding the individual's cortisol awakening response pattern, healthcare providers can tailor personalized stress management strategies, lifestyle modifications, and relaxation techniques to optimize adrenal health and resilience to stress.
  4. Insight into Fatigue and Energy Levels: Dysregulated cortisol levels, particularly in the morning, can contribute to fatigue, low energy levels, and difficulties with concentration and focus. Assessing the CAR can provide insights into potential causes of fatigue and guide interventions to improve energy levels and overall well-being.
  5. Early Detection of Health Risks: Abnormalities in the CAR may be associated with various health conditions, including mood disorders, anxiety, depression, metabolic syndrome, and cardiovascular disease. Early detection through cortisol assessment can facilitate early intervention and preventive measures.
  6. Monitoring Treatment Effectiveness: For individuals undergoing treatment for stress-related conditions or adrenal dysfunction, regular monitoring of the CAR can help assess the effectiveness of interventions, such as stress reduction techniques, dietary modifications, hormone therapy, or supplementation.
  7. Non-invasive Testing: Saliva sampling for cortisol measurement is non-invasive and can be easily performed at home, providing convenience for the individual undergoing testing.

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