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Cortisol Blood Test, Random Serum

This Cortisol Blood Test detects excess or deficient cortisol production.

Sample Report

Test Code: 004051

Also Known As:

Methodology: Electrochemiluminescence immunoassay (ECLIA)

Preparation: No fasting required. Stop biotin consumption at least 72 hours prior to the collection.

Test Results: 1-2 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 367

Also Known As:

Methodology: Immunoassay (IA)

Preparation: No fasting required. Stop biotin consumption at least 72 hours prior to the collection.

Test Results: 1-2 days. May take longer based on weather, holiday or lab delays.

Description

Cortisol, the major adrenal glucocorticoid steroid hormone, is usually under feedback control by pituitary ACTH and the hypothalamus. Causes of low cortisol include pituitary failure or destruction, with resultant loss of ACTH to stimulate the adrenal, and metabolic errors or destruction of the adrenal gland itself (adrenogenital syndromes, tuberculosis, histoplasmosis). The diagnosis of hypoadrenalism usually requires confirmation with ACTH stimulation, due to the circadian rhythms of cortisol and other factors. Causes of increased cortisol, which may initially present as simply a loss of normal diurnal variation, include pituitary overproduction of ACTH, production of ACTH by a tumor (notably oat cell cancers), and adrenal adenomas.

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