Estrogen Metabolites, Urine - Doctor's Data Test Kit

What is the purpose of this test?

The Estrogen Metabolites, Urine - Doctor's Data Test Kit provides a detailed analysis of how the body processes and breaks down estrogen. Estrogen metabolism is an essential factor in overall hormone balance, influencing reproductive health, metabolism, and the risk of hormone-related conditions. This test measures the three primary estrogens—estrone (E1), estradiol (E2), and estriol (E3)—along with their metabolites to help evaluate hormone function and detoxification pathways. Since estrogen breakdown depends on liver function, this test can also offer insight into how effectively the liver is processing hormones and whether harmful byproducts are accumulating.

By examining estrogen metabolites, this test helps determine if the body is favoring safer pathways or producing potentially harmful compounds linked to oxidative stress and DNA damage. The results can assist in evaluating hormonal imbalances, monitoring the effects of hormone replacement therapy (HRT/BHRT), and identifying potential risks associated with estrogen dominance. Since estrogen metabolism is influenced by factors such as genetics, liver function, diet, and lifestyle, understanding these patterns can help guide personalized health strategies.

The Estrogen Metabolites, Urine - Doctor's Data Test Kit includes:

• Primary Estrogens & Metabolites:
  • Estrone (E1), Estradiol (E2), Estriol (E3)
• Hydroxyestrogen Metabolites (Phase I Metabolism):
  • 2-Hydroxyestrone (2-OH-E1)
  • 4-Hydroxyestrone (4-OH-E1)
  • 16a-Hydroxyestrone (16-OH-E1)
  • 2-Hydroxyestradiol (2-OH-E2)
  • 4-Hydroxyestradiol (4-OH-E2)
• Methylated Metabolites (Phase II Detoxification):
  • 2-Methoxyestrone (2-M-E1)
  • 4-Methoxyestrone (4-M-E1)
  • 2-Methoxyestradiol (2-M-E2)
• Additional Marker:
  • Creatinine/day (used for urine concentration normalization)

Who should get this test?

This test is beneficial for individuals experiencing or monitoring:

Women:

• Menopausal symptoms
• Breast health concerns
• Endometriosis
• Polycystic Ovary Syndrome (PCOS)
• Premenstrual Syndrome (PMS) or Premenstrual Dysphoric Disorder (PMDD)

Men:

• Breast health concerns
• Prostate health concerns
• Erectile dysfunction

General Health Conditions:

• Metabolic syndrome
• Thyroid disorders
• Chronic inflammation
• Mood imbalances (such as anxiety or depression)
• Family history of hormone-driven cancers (breast, ovarian, prostate)
• Use of hormone replacement therapy (HRT/BHRT)
• Unexplained weight gain or difficulty losing weight

Benefits of the Estrogen Metabolites, Urine - Doctor's Data Test Kit:

1. Comprehensive Hormone Analysis – Evaluates estrogen metabolism and detoxification pathways to identify potential imbalances.
2. Insight into Breast & Prostate Health – Helps assess estrogen-related cancer risks by examining key estrogen metabolites.
3. Guidance for HRT/BHRT Monitoring – Supports individuals using hormone therapy by evaluating how their body processes estrogens.
4. Liver Detoxification Evaluation – Provides insight into liver function and how well estrogen is being metabolized and cleared.
5. Risk Assessment for DNA Damage – Identifies harmful estrogen byproducts that could contribute to oxidative stress and genetic mutations.
6. Personalized Treatment Planning – Helps healthcare providers recommend lifestyle, dietary, and supplement interventions to support healthy estrogen metabolism.
7. Non-Invasive Testing – Requires only four or five urine collections, making it an easy and convenient option for hormone assessment.

This test is a valuable tool for anyone looking to better understand their hormone health, optimize treatment plans, or assess potential health risks related to estrogen metabolism.