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Fecal Lactoferrin Stool Add-On - Genova Test Kit

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The Fecal Lactoferrin Stool Add-On - Genova Test Kit identifies intestinal inflammation, detects active IBD, differentiates between IBD and non-inflammatory conditions, and monitors IBD progress.


Test Code:






Ship test kits to the lab Monday-Thursday only. No fasting is required for collection. However, before collecting a sample for fat absorption assessment, patients should consume their normal dietary fat intake. It is recommended to wait at least two weeks after completing medications such as PPIs, bismuth, antifungals, antibiotics, probiotics, and anti-parasitics. Patients should avoid taking digestive enzymes, laxatives (particularly mineral or castor oil), antacids, aspirin, and substances containing barium or bismuth for at least 48 hours before and during specimen collection. Consult with your physician before stopping any medications.

Test Results:

14 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.

What is the purpose of this test?

Order this Fecal Lactoferrin Stool Add-On - Genova Test Kit, which can detect inflammation in the intestines, determine if inflammatory bowel disease (IBD) is active, differentiate between IBD and non-inflammatory bowel conditions, and track the activity of IBD. 


Lactoferrin is a protein produced by a specific type of white blood cell known as neutrophils. When there's inflammation in the digestive tract, neutrophils are attracted to the affected area and release lactoferrin. The protein levels in the stool are then elevated. This test is designed to measure the amount of lactoferrin in the stool, which can indicate inflammation in the intestines. 


Individuals should note that this test kit is only offered as an add-on test for:

  • Genova Diagnostic's Gastrointestinal (GI) Effects Comprehensive Stool Profile 1-Day Test Kit (GD2200)
  • Gastrointestinal (GI) Effects Comprehensive Stool Profile 3-Day Test Kit (GD2201)
  • Gastrointestinal (GI) Effects Microbial Ecology Stool Profile (GD2205)

Don't hesitate to contact Walk-In Lab's Customer Service at 1-800-539-6119 if you are interested in this add-on test, as additional charges will be applied.


What conditions are related to abnormal fecal lactoferrin levels?

Inflammatory bowel disease (IBD) and certain bacterial infections of the digestive tract are linked with intestinal inflammation. However, this condition is not associated with other disorders that cause similar symptoms and affect bowel function. To differentiate between inflammatory and non-inflammatory conditions, lactoferrin can be utilized.


Inflammatory bowel disease (IBD) is a collection of chronic disorders that cause inflammation and damage the tissues lining the intestinal tract. The exact cause of IBD remains unknown, but it is thought to result from an autoimmune response triggered by genetic predisposition, viral infections, or environmental factors.


The two most prevalent types of IBD are:


  • Crohn's disease (CD) 
  • Ulcerative colitis (UC)


When should I order a Fecal Lactoferrin Stool Add-On - Genova Test Kit?

Individuals may order this add-on test if they have experienced symptoms related to intestinal inflammation or IBD. Those with IBD often experience periods of active disease followed by periods of remission. During a flare-up, symptoms may include:


  • Frequent episodes of watery or bloody diarrhea
  • Abdominal pain
  • Weight loss
  • Fever


However, symptoms frequently subside between flare-ups, and many individuals may experience extended periods of remission. To monitor disease activity, lactoferrin testing can be a useful tool.

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