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Fibrinogen Activity Blood Test

The Fibrinogen Activity Test is used to check for fibrinogen, coagulation factor, a protein that is essential for blood clot formation.

Sample Report

Test Code: 001610

Also Known As: Clottable Fibrinogen; Factor I Activity

Methodology: The measurement of fibrinogen activity is based on determination of fibrin polymerization function by the Clauss method.10 This method measures the rate of clot formation after adding a high concentration of thrombin to citrated plasma. The fibrinogen activity is then derived from a standard curve relating the clotting time to plasma standards of known fibrinogen activity.

Preparation: No special preparation required.

Test Results: 2-3 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 461

Also Known As: Clottable Fibrinogen; Factor I Activity

Methodology: Photometry/Optical, Clauss

Preparation: No special preparation required.

Test Results: 2-3 days. May take longer based on weather, holiday or lab delays.

Description

A Fibrinogen activity blood test from Walk-In Lab is typically ordered to help assess the cause of blood disorders (often problems with blood clotting) or thrombotic episodes. Additionally, patients order this blood test alongside other labs that test for cardiac risk or to aid in the monitoring of a progressive disease or the progress of an acquired condition.

The Fibrinogen Activity Blood Test is also known as Factor I Activity and Clottable Fibrinogen. Patients are not required to fast when preparing for this lab and results are typically available within two to three days.

Fibrinogen, a protein essential for blood clot formation, is produced by the liver and released as needed into the bloodstream. Typically, when a blood vessel wall or body tissue is injured, the coagulation cascade activates fibrinogen and more than 20 other clotting factors, one after the other. As the cascade nears completion, soluble fibrinogen changes into insoluble fibrin threads. The threads crosslink to form a fibrin net that stabilizes at the site of injury. The fibrin net adheres to the site of injury, along with platelets, and forms a stable blood clot. This blood clot serves as a barrier and prevents additional blood loss.  The clot remains in place until the injured area heals completely. Fibrinogen is one of many blood factors called acute phase reactants. Along with other acute phase reactants, blood levels of fibrinogen rise sharply with some conditions, causing acute tissue inflammation or damage. A fibrinogen test measures the amount of soluble Factor I (which is fibrinogen dissolved in the blood) before it has turned into insoluble fibrin and crosslinked into a fibrin net.

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