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Hypersensitivity Pneumonitis Evaluation

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The Hypersensitivity Pneumonitis Evaluation detects specific antibodies in the blood to help diagnose hypersensitivity pneumonitis.


Test Code:


CPT Code(s):



Double Diffusion (DD) • ImmunoCAP®




No special preparation is required.

Test Results:

4-8 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI

The Hypersensitivity Pneumonitis Evaluation includes the following analytes:

  • Aspergillus fumigatus
  • S. rectivirgula
  • T. candidus
  • T. sacchari
  • T. vulgaris
  • Saccharomonospora viridis
  • Aureobasidium pullulans (m12) IgG
  • Alternaria alternata (m6) IgG
  • Cladosporium herbarum (m2) IgG
  • Penicillium notatum (m1) IgG
  • Phoma spp IgG
  • Trichoderma viride (m15) IgG


What is the purpose of this test?

If you suspect you may be suffering from hypersensitivity pneumonitis, a condition that causes inflammation of the lungs due to an allergic reaction, you can order a blood test to aid in its diagnosis. The test can detect specific antibodies in your blood and determine the various allergens that may trigger your symptoms, such as animal and plant proteins, bacteria, fungi, and more. It is crucial to address hypersensitivity pneumonitis early on, as chronic cases can result in permanent lung damage and scarring.


What causes hypersensitivity pneumonitis?

If you work in an environment with a high concentration of organic dust, fungus, or molds, you may risk developing hypersensitivity pneumonitis. This respiratory condition can cause inflammation in the lungs and eventually lead to acute lung disease if you are exposed to these irritants for prolonged periods. Unfortunately, even humidifiers, heating systems, and air conditioners in your home or office may contain fungi or bacteria that could trigger this condition. Additionally, exposure to certain chemicals such as isocyanates or acid anhydrides can also put you at risk. Therefore, it is crucial to be aware of these potential hazards and take necessary steps to safeguard yourself if you are at risk.


Examples of hypersensitivity pneumonitis include:

Bird fancier's lung: One of the most prevalent forms of hypersensitivity pneumonitis is caused by frequent or intense contact with proteins present in the feathers or excrement of various bird species.


Farmer's lung: Exposure to dust from moldy hay, straw, and grain can cause a specific type of hypersensitivity pneumonitis.


When should I order a Hypersensitivity Pneumonitis Evaluation?

Individuals may order this test if they have experienced symptoms related to hypersensitivity pneumonitis. Common signs or symptoms of hypersensitivity pneumonitis include:


  • Chills
  • Cough
  • Fever
  • Malaise (feeling ill)
  • Shortness of breath
  • Loss of appetite
  • Sudden weight loss

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