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Methylated Septin 9 Blood Test, ColoVantage

The methylated septin 9 blood test is used to detect circulating methylated DNA from the septin 9 (SEPT9) gene.  It is also used in the detection of colorectal cancer in patients non-adherent to current testing methods.

Sample Report

Test Code: 16983

Also Known As: methylated septin 9 DNA; methylated SEPT9 DNA; SEPT9

Methodology: Real-Time Polymerase Chain Reaction

Preparation: No special preparation required.

Test Results: 9-12 days. May take longer based on weather, holiday or lab delays.


The methylated septin 9 test is a sensitive blood-based colorectal cancer screening test using the SEPT9 biomarker.  This test specifically detects a majority of colorectal cancer of all stages and colorectal locations. The test is an alternative for those who are unwilling to undergo a colonoscopy.

About half of Americans 50 to 75 years old do not follow recommended colorectal cancer screening guidelines, leaving 40 million individuals unscreened. A simple blood test would increase screening compliance, promoting early detection and better patient outcomes. 

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