Mumps Blood Test, IgG
This Mumps Blood Test, IgG is to determine immunity to the mumps.
Mumps is an acute, usually self-limited systemic illness characterized by parotidites, high fever and fatigue. One third of infections are asymptomatic. A live attenuated vaccine is available. The mumps EIA IgG antibody test is sufficiently sensitive to establish immune status of the patient.
A positive result indicates that the patient has antibody to mumps virus. It does not differentiate between an active or past infection. The clinical diagnosis must be interpreted in conjunction with clinical signs and symptoms of the patient.
IgG alone is not diagnostic unless you obtain both an acute (can be done as soon after onset as seen, but ideally four to five days after onset of symptoms) and convalescent (from two to three weeks after onset) blood specimen for serologic tests to determine if a four-fold rise in IgG antibody titer has occurred (e.g., from 1:40 to 1:320). A four-fold increase in IgG titer as is measured in plaque-reduction neutralization assays or similar quantitative assays, or a seroconversion from negative to positive in EIA assays from acute to convalescent is considered to be a positive diagnostic result for mumps.
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