Myeloperoxidase MPO Blood Test

What is the purpose of this test?

Order this Myeloperoxidase (MPO) Blood Test, which screens for inflammation in blood vessels by measuring MPO levels in a blood sample. Elevated levels of MPO are often linked to inflammation in the blood vessels, which could indicate an increased risk of cardiovascular diseases, including coronary artery disease. The Cardio IQ® Myeloperoxidase test provides specific information about vascular inflammation, which can be an early sign of plaque rupture and subsequent heart attack. 

What conditions are associated with abnormal MPO levels?

Abnormal MPO levels are indicative of a heightened risk for the following coronary conditions:

• Coronary Artery Disease (CAD): A condition where plaque builds up in the arteries supplying blood to the heart, which can cause acute coronary events.
• Acute Coronary Syndromes: Any sudden blockage or reduced blood flow to the heart that causes conditions like heart attacks or unstable angina.

It is also important to note that:

• Individuals with elevated MPO levels are more than 2x as likely to experience cardiovascular mortality.
• Elevated MPO levels indicate a high risk of heart disease in subgroups with cholesterol results associated with low risk.
• Elevated MPO levels are not a result of chronic infections or rheumatologic disorders since MPO in the blood is a specific marker of vascular inflammation and vulnerable plaque.

When should I order a Myeloperoxidase (MPO) Blood Test?

Individuals may order this test if they have experienced symptoms related to CAD or acute coronary events. Common signs or symptoms of these conditions may include: 

• Chest pain
• Pain in the back, shoulders, neck, arms, or abdomen
• Feeling hot or flushed
• Feeling dizzy or lightheaded
• Abnormal heart rate
• Shortness of breath
• Fatigue and weakness
• Rashes or ulcers
• Nausea or vomiting