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Myocardial Antibody Screen Blood Test

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The Myocardial Antibody Screen with Reflex to Titer Blood Test detects myocardial antibodies to screen for autoimmune myocarditis.


Test Code:


CPT Code(s):



Indirect Immunofluorescence




No special preparation is required.

Test Results:

8-10 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI

What is the purpose of this test?

The Myocardial Antibody Screen with Reflex to Titer Blood Test is a diagnostic tool used to detect the presence of specific antibodies in the blood that could indicate the presence of certain autoimmune diseases. This test is primarily used to identify myocardial antibodies, which are associated with autoimmune myocarditis, a condition where the immune system mistakenly attacks the heart muscle.


The test works by measuring the level of antibodies in the blood. If the initial screen is positive, the test reflexes to a titer, which measures the concentration of antibodies in the blood. A high titer value indicates a high concentration of antibodies in the blood, which may indicate a more severe case of autoimmune myocarditis.


The benefits of this test for patients are numerous. Early detection of autoimmune myocarditis can lead to prompt treatment, which can help prevent serious complications like heart failure, arrhythmias, and sudden cardiac death. Additionally, identifying the presence of myocardial antibodies can help healthcare providers determine the underlying cause of symptoms like chest pain, shortness of breath, and fatigue, leading to a more accurate diagnosis and appropriate treatment plan.


What conditions are associated with the presence of myocardial antibodies?

The presence of myocardial antibodies has been associated with several conditions, such as:


  • Myocarditis
  • Dilated cardiomyopathy
  • Rheumatic fever
  • Dressler's syndrome
  • Chagas disease


However, the presence of these antibodies alone does not necessarily indicate the presence of any of these conditions. Consulting with a healthcare provider for proper diagnosis and treatment is important.


When should I order a Myocardial Antibody Screen with Reflex to Titer Blood Test?

Individuals may order this test if they have experienced symptoms related to autoimmune myocarditis. Common signs or symptoms of autoimmune myocarditis include:


  • Chest pain
  • Shortness of breath
  • Fatigue
  • Rapid or irregular heartbeat
  • Swelling in the legs, ankles, or feet
  • Fainting or lightheadedness
  • Fluid buildup in the lungs
  • Sudden cardiac arrest (in severe cases)

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