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NeuroGenomic™ Buccal Swab Profile - Genova Test Kit

This test evaluates single nucleotide polymorphisms (SNPs) in genes that modulate methylation, glutathione conjugation, oxidative protection, and the potential to evaluate vascular oxidation.

Test Code: GD5005

Also Known As:

Methodology:

Preparation: No fasting required. Ship to lab Monday-Thursday only. Specimen must be collected immediately upon rising. The night before collection you may brush and floss teeth, but do not use mouthwash. On the morning of collection, do not eat, brush or floss your teeth, use mouthwash, chew gum or use any tobacco, or coffee products. You may drink ONLY water before specimen collection. Just prior to collection, wash hands completely with hand soap.

Test Results: 21 days once the lab receives the specimen. May take longer based on weather, holiday or lab delays.

Description

This test uncovers potential genetic susceptibility to:

  • Detoxification Capacity
  • Neurodegenerative Disorders
  • Oxidative Stress
  • Developmental Issues
  • Mood Disorders

Methylation

  • MTHFR 
  • COMT

These genes influence how homocysteine and methionine are metabolized to support the formation of SAMe.  The ability to donate methyl groups affects neurologic function and is modifiable by proper B-vitamin intake.

Detoxification

  • GSTM
  • GSTP
These genes are responsible for detoxifying products of oxidative stress and carcinogens. Variants decrease detoxification capacity.
 
Oxidative Protection
  • SOD-2
These genetic variants alter anti-oxidant enzyme activity and modify requirements for anti-oxidants.

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