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Organic Acid Analysis Urine Test, Random

The Organic Acid Analysis Urine Test, Random detects abnormal levels of organic acids to help screen for rare inborn errors of metabolism.

Sample Report

Test Code: 716720

CPT Code: 83919

Also Known As:


Gas Chromatography/Mass Spectrometry (GC/MS)

Specimen Type: Urine


No special preparation is required.

Test Results:

3-7 days. May take longer based on weather, holiday, or lab delays.


What are organic acids?

Organic acids are chemical compounds (metabolites) expelled in the urine that are byproducts of metabolism. Metabolism is the series of chemical reactions the body uses to convert food into cellular energy. The organic acids produced as a result of this process help the body to yield cellular energy and provide many building blocks necessary for cell function. Organic acids are acidic organic compounds in which carbon and hydrogen are always present but may also contain the elements of oxygen, nitrogen, sulfur, and phosphorus. Additionally, organic acids are produced from gut microbiome metabolism, neurotransmitter metabolism, and during detoxification. 


What is the purpose of this test?

Order this Organic Acid Analysis Urine Test, Random to detect abnormal levels of organic acids to help screen for rare inborn errors of metabolism. Organic acid levels in the urine are typically more concentrated than in the blood, making them easier to measure and analyze.


What can cause abnormal organic acid levels?

An error in the metabolic pathway can result in either excess or deficient levels of organic acids and other byproducts. Thus, assessing organic acid levels can help determine if metabolic processes are blocked or vulnerable. In addition, this test can provide insight into the potential need for support in gut health and metabolism.


Several disorders can affect the body's metabolic processes. These disorders can be hereditary or caused by factors such as:


  • Side effects of certain medications
  • Drug abuse
  • Malnutrition
  • Diet (High-protein, high carbohydrate and sugar, and sulfates)
  • Stress
  • Antibiotics
  • Some types of cancer


When should I order an Organic Acid Analysis Urine Test, Random?

Metabolic disorders can cause a variety of symptoms, including but not limited to the following:


  • Unusual fluctuations in blood sugar
  • Lethargy
  • Hyperactivity
  • Dry skin
  • Anemia
  • Weight loss or gain
  • Frequent infections
  • Impaired hearing or vision
  • Nausea
  • Heart failure

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