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Osteocalcin Blood Test

An Osteocalcin Blood Test is used to test the osteocalcin protein that is found in bone and teeth.

Sample Report

Test Code: 010249

Also Known As: Bone GLA Protein; bone gamma-carboxyglutamic acid-containing protein; N-MID osteocalcin; BGLAP

Methodology: Enzyme-linked immunosorbent assay (ELISA)

Preparation: No fasting required. Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Test Results: 2-3 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 16322

Also Known As: Bone GLA Protein; bone gamma-carboxyglutamic acid-containing protein; N-MID osteocalcin; BGLAP

Methodology: Electrochemiluminescence (ECLIA)

Preparation: No fasting required. Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Test Results: 4-7 days. May take longer based on weather, holiday or lab delays.

Description

Osteocalcin is a protein found in bone and teeth. It is secreted by bone-building cells, called osteoblasts, and is deposited inside the bone matrix.  Serum osteocalcin represents the fraction of the total produced that has not been placed inside the bone matrix.

Osteocalcin is often used as a biochemical marker, or biomarker, for the bone formation process. It has been routinely observed that higher serum osteocalcin levels are relatively well correlated with bone diseases characterized by increased bone turnover, especially osteoporosis.

In many studies, osteocalcin is used as a preliminary biomarker on the effectiveness of bisphosphonates, a class of drugs used to treat osteoporosis.

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