Phosphatidylethanol (PEth) Blood Test

What is the purpose of this test?

The Phosphatidylethanol (PEth) Blood Test is a highly specific and sensitive test used to detect recent and chronic alcohol use. Unlike traditional alcohol tests that measure ethanol in breath, urine, or blood (which can disappear within hours), the PEth test measures a direct alcohol biomarker that stays in the blood for up to 2 to 4 weeks after alcohol consumption. PEth is formed only in the presence of ethanol, which makes it an ideal marker for determining alcohol intake with high accuracy and low risk of false positives.

This test is often used in clinical settings, legal cases, substance use treatment programs, and workplace testing where monitoring alcohol use is necessary. Because PEth levels correlate with the amount and frequency of alcohol consumed, the test can help healthcare providers assess patterns of drinking behavior. It can also support treatment planning and provide proof of abstinence or confirm suspected alcohol misuse. The Phosphatidylethanol test is especially helpful when honesty about drinking habits is in question or when precise monitoring is required for recovery or court compliance.

Who should get this test?

The Phosphatidylethanol (PEth) Blood Test may be helpful for:

• Individuals undergoing alcohol recovery treatment who need to demonstrate sobriety.
• People involved in child custody, legal, or workplace situations that require alcohol monitoring.
• Healthcare providers looking to assess chronic or excessive alcohol use in patients.
• Individuals with liver disease, pancreatitis, or other alcohol-related conditions.
• Anyone with a personal or family history of alcohol use disorder who wants to monitor consumption.
• Employers or professionals in safety-sensitive positions requiring alcohol screening.

When should I order the Phosphatidylethanol (PEth) Blood Test?

Individuals may consider ordering this test if they have symptoms or exposure concerns related to alcohol use.

Symptoms to consider:

• Mood changes, anxiety, or irritability.
• Memory problems or trouble concentrating.
• Digestive problems like nausea, bloating, or vomiting.
• Fatigue, shakiness, or tremors.
• Liver issues, such as jaundice or abnormal liver enzymes.
• Frequent alcohol use despite health, legal, or relationship problems.

If you have these symptoms or suspect unhealthy drinking habits, the Phosphatidylethanol (PEth) Blood Test can provide valuable information to help you and your doctor assess alcohol use patterns, support recovery goals, or meet legal or workplace testing requirements.