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Prostate-specific Antigen (PSA) Blood Test Free:Total Ratio (Serial Monitor)

The PSA Blood Test Free:Total Ratio is a PSA screening test that includes % Free and Serial Monitor report.

Sample Report

Test Code: 480780

CPT Code: 84153,84154

Also Known As:


The patient plasma is added to PS-depleted normal plasma with normal levels of all factors but PS. The mixture is supplemented with excess aPC and factor V is then added. The extent of prolongation of the time to clot formation after calcium chloride is added is proportional to plasma PS activity.

Specimen Type: Blood


No special preparation required.

Test Results:

4-5 days. May take longer based on weather, holiday or lab delays.


Most PSA tests measure "total PSA," or the amount that is bound to blood proteins. In March, FDA approved the Tandem R test, which measures not only total PSA but another component called "free PSA," which floats unbound in the blood. Comparing the two helps doctors rule out cancer in men whose PSA is mildly elevated from other causes. A 1995 study in the Journal of the American Medical Association showed that the free PSA test can reduce unnecessary prostate biopsies by 20 percent in patients with a PSA between 4 and 10.

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