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Protein C Functional Blood Test

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The Protein C Functional Blood Test is used to help investigate a possible clotting disorder.

LabCorp

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Test Code:

117705

CPT Code(s):

85303

Also Known As:

Functional Protein C; Protein C, Functional, Plasma; Protein C, Functional Blood Test; Protein C Activity (Chromogenic)

Methodology:

A specific enzyme extracted from the venom of Agkistrodon c. contortrix is used to activate PC in the patient sample. All other factors required for normal aPTT are supplied in the reagent. The activated protein C inhibits factors V and VIII in the reagent and the resultant prolongation of the aPTT-based clotting time is proportional to plasma PC activity.

Specimen:

Blood, Plasma

Preparation:

No fasting required. Ideally, patients should not be on anticoagulant therapy. Avoid warfarin therapy 2 weeks before blood draw. Avoid heparin, direct Xa, and thrombin inhibitor therapies for 3 days before blood draw. Check with physician before stopping any medications.

Test Results:

5-7 days. May take longer based on weather, holiday or lab delays.

Walk-In Lab is prohibited from selling LabCorp tests to residents in the following states:NY, NJ, RI, MA, MD

Quest

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Sample Report Compare
Test Code:

1777

CPT Code(s):

85303

Also Known As:

Functional Protein C; Protein C, Functional, Plasma; Protein C, Functional Blood Test; Protein C Activity (Chromogenic)

Methodology:

Clotting Assay

Specimen:

Blood, Plasma

Preparation:

No fasting required. Ideally, patients should not be on anticoagulant therapy. Avoid warfarin therapy 2 weeks before blood draw. Avoid heparin, direct Xa, and thrombin inhibitor therapies for 3 days before blood draw. Check with physician before stopping any medications.

Test Results:

5-7 days. May take longer based on weather, holiday or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI


Protein C is a blood test that is also ordered with other blood tests like Protein S to investigate a possible excessive clotting disorder. This test should not be used for patients receiving thrombin inhibitors such as hirudin and argatroban.

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