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sdLDL Blood Test

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The sdLDL Blood Test measures sdLDL levels in the blood to help assess an individual's risk of developing atherosclerosis or cardiovascular disease.


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Test Code:


CPT Code(s):







Fasting may be required for this test. Please ask your doctor if you should fast prior to testing.

Test Results:

3-5 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI

What is sdLDL?

LDL, or low-density lipoprotein, is often referred to as "bad cholesterol" because it can build up in the walls of arteries, leading to atherosclerosis and an increased risk of heart disease. However, not all LDL particles are created equal. Some studies suggest that small, dense LDL particles (sdLDL) may be even more harmful than larger LDL particles. This is because sdLDL can more easily penetrate the walls of arteries and contribute to plaque buildup. People with insulin resistance, diabetes, and metabolic syndrome are more likely to have higher levels of sdLDL.


What is the purpose of this test?

The sdLDL blood test is a specialized diagnostic tool used to measure the amount of small, dense, low-density lipoprotein (sdLDL) particles in the blood. These particles are considered more harmful than larger, less dense LDL particles, as they are more likely to contribute to plaque buildup in the arteries. This plaque buildup can lead to atherosclerosis, a condition in which the arteries become narrowed and hardened, potentially resulting in heart disease, heart attack, or stroke. The sdLDL blood test is typically recommended for people who are at risk of developing cardiovascular disease, such as those with a family history of heart disease, high blood pressure, or high cholesterol. In addition, the test may be used to monitor the effectiveness of cholesterol-lowering medications or lifestyle changes in reducing the amount of sdLDL in the blood.

During the sdLDL blood test, a healthcare professional will draw a small blood sample from the patient's arm. The sample is then sent to a laboratory, where the amount of sdLDL is measured using specialized techniques. Based on the test results, healthcare professionals can assess a person's risk of developing cardiovascular disease and make recommendations for lifestyle changes or interventions to reduce that risk. These recommendations may include changes to the person's diet, exercise habits, or medication regimen, as well as regular monitoring of their cholesterol levels and other cardiovascular risk factors.


When should I order an sdLDL Blood Test?

Individuals may order this test if they have an increased risk of developing cardiovascular disease. These risk factors include:

  • High blood pressure
  • High cholesterol levels
  • Smoking
  • Obesity or being overweight
  • Physical inactivity or a sedentary lifestyle
  • Unhealthy diet
  • Diabetes or insulin resistance
  • Family history of cardiovascular disease
  • Age (risk increases with age)
  • Gender (men have a higher risk than women)
  • Stress and poor mental health
  • Excessive alcohol consumption

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