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Serotonin Blood Test

The Serotonin Blood Test is ordered to help diagnose and monitor treatment for a serotonin-secreting carcinoid tumor.

Sample Report

Test Code: 120204

Also Known As: 5-HT, Serum; 5-HT; 5-Hydroxytryptamine, Serum; 5-Hydroxy Tryptamine;

Methodology: High-pressure liquid chromatography (HPLC) with electrochemical (EC) detection

Preparation: No fasting required. Avoid food high in indoles such as avocado, banana, tomato, plum, walnut, pineapple, and eggplant. Tobacco, tea and coffee should also be avoided three days prior to specimen collection. Serotonin levels may be affected by certain types of medications such as morphine, MAO inhibitors, methyldopa, and lithium. Check with physician before stopping any medications.

Test Results: 3-4 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 29851

Also Known As: 5-HT, Serum; 5-HT; 5-Hydroxytryptamine, Serum; 5-Hydroxy Tryptamine;

Methodology: Fluorescence Detection • High Performance Liquid Chromatography (HPLC)

Preparation: No fasting required. Avoid food high in indoles such as avocado, banana, tomato, plum, walnut, pineapple, and eggplant. Tobacco, tea and coffee should also be avoided three days prior to specimen collection. Serotonin levels may be affected by certain types of medications such as morphine, MAO inhibitors, methyldopa, and lithium. Check with physician before stopping any medications.

Test Results: 4-11 days. May take longer based on weather, holiday or lab delays.

Description

Serotonin, a chemical, is derived from the amino acid tryptophan. It is produced as necessary by the nervous system, mainly the brain, but also by special cells in the bronchial tubes (lungs) and gastrointestinal tract. In the blood, most serotonin, more than 90%, is found in the platelets. Serotonin helps constrict blood vessels and transmit nerve impulses, aids in the wake-sleep cycle, and affects mood. It is metabolized by the liver and its metabolites, primarily 5-HIAA (5-hydroxyindoleacetic acid, a muscle stimulant), are then excreted in the urine. Serotonin is normally present in small varying quantities in the blood, and large quantities of serotonin and 5-HIAA may be produced continuously or intermittently by some carcinoid tumors.

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