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Sex Steroid Metabolites Profile, Dried Urine - ZRT Test Kit

The Sex Steroid Metabolites Profile, Dried Urine - ZRT Test Kit assesses various hormone levels to help monitor adrenal dysfunction, hormone therapy, and breast cancer risk.

Test Code: ZRTSSM

Also Known As:


Specimen Type: Dried Urine


Patients should not eat, drink (except water) or brush their teeth prior to their first collection of the day and for the 2 hours prior to collecting throughout the day. Refrain from drinking more than 8 oz water the hour before each dried urine strip collection to allow urine to concentrate. Patients should also avoid anti-aging/anti-wrinkle facial creams for at least 3 days prior to testing as they may contain undisclosed hormones.

Test Results:

5-7 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.


The Sex Steroid Metabolites Profile, Dried Urine measures the following analytes:

  • Estrogens (13): Estradiol (E2) | Estrone (E1) | Estriol (E3) | 2-Hydroxy Estradiol (2-OH E2) | 2-Hydroxy Estrone (2-OH E1) | 4-Hydroxy Estradiol (4-OH E2) | 4-Hydroxy Estrone (4-OH E1) | 16α-Hydroxy Estrone (16α-OH E1) | 2-Methoxy Estradiol (2-MeO E2) | 2-Methoxy Estrone (2-MeO E1) | 4-Methoxy Estradiol (4-MeO E2) | 4-Methoxy Estrone (4-MeO E1) | Bisphenol A (BPA)


  • Progestogens (7): Pregnanediol (Pgdiol) | Allopregnanolone (AlloP) | Allopregnanediol (AlloPd) | 3α-Dihydroprogesterone (3αHP) | 20α-Dihydroprogesterone (20αHP) | Deoxycorticosterone (DOC) | Corticosterone (Ccn)


  • Androgens (8): DHEA (D) | Androstenedione (Adione) | Androsterone (Andro) | Etiocholanolone (Etio) | Testosterone (T) | Epi-Testosterone (Epi-T) | 5α-Dihydrotestosterone (5α-DHT) | 5α,3α-Androstanediol (5α3α)


  • Glucocorticoids (4): Total Cortisol (TC) | Total Cortisone (TCn) | Tetrahydrocortisol (ThC) | Tetrahydrocortisone (ThCn) 


  • Creatinine


What is the purpose of this test?

Order this Sex Steroid Metabolites Profile, Dried Urine, which monitors adrenal dysfunction, hormone therapy, and breast cancer risk by evaluating various hormone levels. The testing of sex steroid metabolites offers a distinct diagnostic perspective that other hormone tests cannot provide. This type of testing reveals how different hormones, such as estrogens, progestogens, androgens, and cortisol, break down in a patient's body. Moreover, it enables healthcare professionals to determine if a patient is effectively detoxifying their hormones, which can make them more or less susceptible to certain diseases such as cancer.


The Sex Steroid Metabolite Profile, Dried Urine would be beneficial for individuals who:

  • Have a risk of developing hormone-dependent cancers.
  • Have a family history of hormone-dependent cancers.
  • Have symptoms of estrogen dominance.
  • Are considering hormone replacement therapy.
  • Are experiencing stress-related symptoms or symptoms of cortisol imbalance.
  • Have normal saliva cortisol levels but are still experiencing symptoms
  • of adrenal dysfunction.

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