Creatinine Clearance 24-Hour Urine and Blood Test With Body Surface Area Normalization
A Creatinine Clearance 24-Hour Urine and Blood Test With Body Surface Area Normalization includes Serum creatinine; urine creatinine.
Also Known As:
Clearance, Creatinine
Specimen:
Blood and urine (24-hour)
Preparation:
You must take your lab order to the lab to obtain a proper specimen container before collection. No fasting required. Drink plenty of water before the clearance is begun, and continue good hydration throughout the clearance. Avoid cephalosporins. If possible, medications should be stopped beforehand. Check with physician before stopping any medications. Urinate at 8am and discard the specimen. Then collect all urine in 24-hour period, ending with final collection at 8am the next morning. Refrigerate the collected urine between all voidings or keep it in a cool place. Screw the lid on securely. Transport the specimen promptly to the laboratory. Container must be labeled with full name, date and time collection started, and date and time collection finished.
Test Results:
3-5 days. May take longer based on weather, holiday or lab delays.
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A creatinine clearance test is used to aid in evaluating the rate and efficiency of kidney filtration. It helps detect kidney dysfunction and/or the presence of decreased blood flow to the kidneys. In patients with chronic kidney disease or congestive heart failure (which decreases the rate of blood flow), a creatinine clearance test may be ordered to monitor the progress of the disease and evaluate severity. The test is also used to evaluate the filtration ability of the kidneys and may be ordered when a patient has increased blood creatinine concentrations, a known or suspected kidney disorder, or decreased blood flow to the kidneys due to a condition such as congestive heart failure.
The amount of creatinine produced by a patient varies according to the lean body mass of the patient. Variations in height and weight could contribute to disparities in the calculated creatinine clearance.1 Normalizing to the patient’s BSA will yield the more clinically useful “corrected creatinine clearance.” The calculation for BSA requires that the patient’s height and weight be supplied
