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17-Hydroxyprogesterone Blood Test, LC/MS-MS

A 17-hydroxyprogesterone blood test, LC/MS-MS is used to screen for, detect, and monitor treatment for congenital adrenal hyperplasia (CAH); sometimes to help rule out other conditions with similar symptoms.

Sample Report

Test Code: 070085

Also Known As: 17-OHP; 17-OH Progesterone; 17-Alpha-Hydroxprogesterone

Methodology: Liquid chromatography/tandem mass spectrometry (LC/MS-MS)

Preparation: No special preparation required.

Test Results: 3-7 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 17180

Also Known As: 17-OHP; 17-OH Progesterone; 17-Alpha-Hydroxprogesterone

Methodology: Chromatography/Mass Spectrometry

Preparation: No special preparation required.

Test Results: 3-7 days. May take longer based on weather, holiday or lab delays.

Description

Markedly elevated in patients with congenital adrenal hyperplasia; evaluate hirsutism or infertility; assess or rule out certain adrenal or ovarian tumors with endocrine activity.

This test may sometimes be ordered in older children or adults when the milder form of CAH (late-onset) is suspected. The 17-OHP test may also be conducted when a female is experiencing symptoms, possibly due to CAH or PCOS. Symptoms may include:

  • Excess facial and body hair (hirsutism)
  • Lack of or irregular menstrual periods (menses)
  • Development of male secondary sex characteristics
  • Infertility

Testing may be performed on boys or men when they experience:

  • Early (precocious) puberty
  • Infertility

When a person has been diagnosed with 21-hydroxylase deficiency, then a 17-OHP test may be ordered periodically to monitor the effectiveness of treatment.

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