Antipancreatic Islet Cells Serum Test
The Antipancreatic Islet Cells Serum Test detects antipancreatic islet cells in a blood sample to help confirm the diagnosis of type 1 diabetes and evaluate the need for insulin treatment.
What are antipancreatic islet cells?
Diabetes is a disease that develops either when the body is not able to make or use insulin appropriately. As a result, the body generates too much blood glucose (sugar) in the bloodstream.
The two primary types of diabetes are:
- Type 1: It happens when the body cannot produce insulin. It is commonly referred to as juvenile diabetes because it is found mainly in children and teenagers. However, type 1 diabetes also affects adults.
- Type 2: It happens when the body cannot make enough insulin or doesn't use it as it should. Although type 2 diabetes is primarily found in adults, many children and teenagers are diagnosed with it.
Antipancreatic Islet Cells are islet cell autoantibodies (ICA) targeted against beta cells in the pancreas. ICAs in people with diabetes suggest that they have autoimmune diabetes (type 1 diabetes). Type 1 diabetes is an autoimmune disease since the lack of insulin stems from an immune response that destroys the insulin-producing beta cells in the pancreas. Approximately 70-80% of individuals with new-onset type 1 diabetes have ICAs. Therefore, a positive result for ICA in asymptomatic individuals or those with a family history may suggest an increased risk of developing type 1 diabetes. In addition, the presence of ICA in the blood of patients who have received a pancreas transplant may imply potential beta-cell failure.
What is the purpose of this test?
Order this Antipancreatic Islet Cells Serum Test to detect antipancreatic islet cells in a blood sample to help confirm the diagnosis of type 1 diabetes. In addition, this test may help healthcare providers evaluate a patient's potential need for insulin treatment.
When should I order an Antipancreatic Islet Cells Serum Test?
Individuals may order this test if they have experienced symptoms related to type 1 diabetes. Signs or symptoms of type 1 diabetes may include:
- Dry mouth
- Frequent urination
- Constant hunger
- Weight loss
- Slow-healing sores or wounds
- Dry or itchy skin
- Numbness or tingling in your feet
- Blurry vision
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