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Cardiolipin Antibodies Blood Test, IgA, IgG, and IgM

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The Cardiolipin Antibodies Blood Test, IgA, IgG, and IgM, detects antibodies in the blood to investigate blood clotting, miscarriage causes, and autoimmune diseases.

LabCorp

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Test Code:

161950

CPT Code(s):

86147(x3)

Methodology:

Enzyme-linked immunosorbent assay (ELISA) detecting isotype-specific ACA binding to a microtiter plate coated with purified cardiolipin antigen

Specimen:

Blood

Preparation:

No special preparation is required.

Test Results:

2-4 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling LabCorp tests to residents in the following states:NY, NJ, RI, MA, MD

Quest

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Sample Report Compare
Test Code:

7352

CPT Code(s):

86147(x3)

Also Known As:

Anticardiolipin Antibodies; aCL Antibody; ACA; Cardiolip; CA; Antiphospholipids;

Methodology:

Immunoassay (IA)

Specimen:

Blood

Preparation:

No special preparation is required.

Test Results:

3-5 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI


What is the purpose of this test?

Order this Cardiolipin Antibodies Blood Test, IgA, IgG, and IgM, which detects antibodies in the blood and investigates inappropriate blood clot formation, recurrent miscarriage, antiphospholipid syndrome, and other autoimmune diseases. 

 

Cardiolipin antibodies are a specific type of autoantibody that recognizes and binds to cardiolipins, which are phospholipids found in cell membranes and platelets. Cardiolipin antibodies have been linked to several medical conditions and complications, including an increased risk of thrombosis, or the formation of blood clots in veins and arteries. This occurs because the antibodies interfere with the body's ability to regulate blood clotting, leading to excessive clot formation. Additionally, cardiolipin antibodies have been associated with thrombocytopenia, a condition in which there are too few platelets in the blood, as well as recurrent miscarriages, premature labor, and pre-eclampsia in pregnant women. 

 

Cardiolipin antibodies are a type of antiphospholipid antibody, which are autoantibodies that target phospholipids in general. These antibodies can cause excessive clotting and may be associated with autoimmune diseases such as lupus. When cardiolipin antibodies are present along with other antiphospholipid antibodies, and there is evidence of inappropriate blood clot formation or recurrent miscarriages, a diagnosis of antiphospholipid syndrome (APS) may be made. This condition can have severe consequences for patients, and early detection and treatment are critical for preventing complications.

 

When should I order a Cardiolipin Antibodies Blood Test, IgA, IgG, and IgM?

Individuals may order this test if they have experienced symptoms related to excessive blood clots. Common signs or symptoms associated with this condition may include:

 

  • Leg pain or tenderness
  • Swollen leg edema
  • Discoloration of the leg
  • Sudden shortness of breath
  • Coughing, hemoptysis (blood present in sputum)
  • Lung-related chest pain
  • Rapid heart rate

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