Chromogranin A Serum Test

What is the purpose of this test?

The Chromogranin A Serum Test measures the level of chromogranin A (CgA), a protein often elevated in certain neuroendocrine tumors, including carcinoid tumors, pheochromocytomas, and pancreatic neuroendocrine tumors. CgA is released by neuroendocrine cells, and its levels in the blood can provide valuable insights into the presence or progression of these conditions.

This test is helpful in diagnosing and monitoring neuroendocrine tumors. It is also used to track treatment effectiveness or detect tumor recurrence. Since other conditions, like chronic atrophic gastritis or kidney disease, can influence CgA levels, your doctor may use this test alongside other clinical evaluations and diagnostic tools.

Who should get this test?

• Individuals with symptoms of neuroendocrine tumors, such as flushing, diarrhea, or rapid heart rate.
• Patients diagnosed with neuroendocrine tumors who need treatment monitoring.
• People with a family history of neuroendocrine or related tumors.
• Individuals with unexplained symptoms that suggest hormonal imbalance or tumor activity.
• Those undergoing treatment for neuroendocrine tumors who require recurrence screening.

When should I order a Chromogranin A Serum Test?

Individuals may consider ordering this test if they have symptoms or concerns related to neuroendocrine tumors. Symptoms to consider:

• Flushing or redness of the skin without an apparent cause.
• Unexplained diarrhea or gastrointestinal discomfort.
• Episodes of rapid heart rate or palpitations.
• Persistent fatigue or unexplained weight loss.
• Hormonal imbalances with unclear causes.

If you experience these symptoms or have a known or suspected neuroendocrine tumor, the Chromogranin A Serum Test can provide important information for diagnosis and treatment planning.