The CICA: Celiac, IBS, and Crohn's Genetic Only - ALCAT Test Kit includes:
- HLA typing for celiac disease
- Genetic biomarkers for Crohn’s disease
What is the purpose of this test?
Order this CICA: Celiac, IBS, and Crohn's Genetic Only - ALCAT Test Kit, which assesses your genetic predisposition to celiac and Crohn's disease, while also evaluating serum markers for active disease. Its purpose is to evaluate gastrointestinal function.
The CICA test uses a single blood draw to analyze genetic predisposition. It can determine the risk of celiac disease by examining the presence or absence of the HLA-DQ genotypes, specifically testing for both the DQ8 and DQ2.5 genotypes. The DQ2.5 genotype is associated with a higher risk of celiac disease. Additionally, the test looks for genetic markers and mutations in the ATG16L1 and NOD2 genes associated with Crohn's disease.
Prevalence of GI issues in the U.S.
Did you know that in the United States, approximately 60-70 million individuals suffer from gastrointestinal disorders? It's interesting to note that celiac disease might be present even if there are no GI symptoms, especially among family members of those with celiac disease.
- In the United States, 40% of Americans suffer from G.I. disorders.
- Ulcerative colitis affects up to 20% of adults in North America.
- It is estimated that around 1% of the general population experiences symptoms of celiac disease.
- Indigestion and constipation are experienced by 15% of individuals in Western countries.
It's not surprising that there is some overlap between these disorders.
Who can benefit from the CICA: Celiac, IBS, and Crohn's Genetic Only - ALCAT Test Kit?
- Individuals experiencing gastrointestinal symptoms and autoimmune disorders that may indicate a gluten-related issue.
- Individuals who have experienced increased intestinal permeability may be at a higher risk for autoimmune disorders and other related conditions.
- Individuals suspected of having Crohn's or celiac disease.
- Individuals experiencing symptoms of IBS, such as diarrhea, bloating, or cramping.
- Individuals with chronic fatigue.
- Individuals who have nutrient malabsorption or deficiency.
- Individuals experiencing unexplained symptoms such as unintentional weight loss or skin rashes.
Preparation:Fasting is not required. You may continue your regular daily medications and supplements. If possible, avoid taking any medications, supplements, IV infusions, or injections for at least 4 hours before your blood draw. If you’re taking medications that affect white blood cell counts, an extra blood tube should be collected. Wait at least 2 weeks after finishing short-term medications like antibiotics before testing.
For tests involving celiac markers (tTg and DGP antibodies), gluten exposure can affect results. Do not intentionally avoid gluten before testing unless you have already been diagnosed with celiac disease. For genetic testing only, gluten intake does not affect results, so no dietary changes are needed. If you have celiac disease, continue your gluten-free diet as directed by your healthcare provider, and consult your doctor to determine if this test is appropriate for monitoring your condition.
Test Results:
7-10 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.
