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Complement C2 Blood Test

A Complement C2 Blood Test is used to assess patients with hereditary deficiency.

Sample Report

Test Code: 161414

CPT Code: 86160

Also Known As: C2 Complement

Methodology: Immunologic quantitation by radial immunodiffusion (RID)

Preparation: No special preparation required.

Test Results: 5-6 days. May take longer based on weather, holiday or lab delays.


C2 is a component of the complement system, a part of the body’s innate immune system. The Complement C2 Serum Test, or simply C2 Blood Test, is ordered to detect and diagnose a deficiency of C2 that could be associated with immune complex and rheumatic diseases. C2 deficiency, which can be hereditary or acquired, is the most common complement deficiency.

Conditions associated with a C2 deficiency include discoid lupus erythematosus (DLE) or systemic lupus erythematosus (SLE), vasculitis (inflammation of the blood vessels), dermatomyositis (inflammation of the muscles and skin), glomerulonephritis (inflammation of the kidneys’ filters), atrophoderma (skin atrophy), cold urticaria (allergy to cold temperatures resulting in skin inflammation), inflammatory bowel disease and recurrent infections. Not all patients with a C2 deficiency will develop such a condition.

Fasting is not required prior to the C2 Blood Test, and results will be available within five to six days. A doctor’s order and insurance are not necessary to purchase this test.

For more information about the complement system, see details on the CH50 Blood Test page. Walk-In Lab also offers  C1q Blood Test and C4 Blood Test.

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