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Methylation Profile Plasma - Doctor's Data Test Kit

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The Methylation Profile Plasma measures the levels of various biomarkers related to the methylation cycle to help detect any imbalances or deficiencies. Note: This is a pre-paid shipping test kit that will be mailed and it requires a blood draw. Please Click Here to locate a lab for specimen collection.


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Test Code:






10-12 hours fasting is required. 48 hours prior to the specimen collection discontinue taking dietary supplements containing methionine, cysteine, and SAMe. Check with physician before stopping medications. Specimen must be sent to the lab by overnight mail Monday-Thursday only. Please read patient instructions very carefully prior to beginning the test.

Test Results:

7-10 days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.

What is the purpose of this test?

The Methylation Profile Plasma - Doctor's Data Test Kit is a comprehensive laboratory test that measures the levels of various substances in the blood that are involved in the methylation process. Methylation is a vital biochemical process that plays a crucial role in many essential functions in the body, such as DNA synthesis, detoxification, and neurotransmitter metabolism. The methylation cycle involves a series of chemical reactions that add or remove methyl groups from molecules, thereby regulating gene expression, protein function, and metabolic pathways.

This test measures the levels of several key biomarkers that are involved in the methylation cycle, including homocysteine, SAM (S-adenosylmethionine), SAH (S-adenosylhomocysteine), and methionine. Elevated levels of homocysteine, for example, have been linked to an increased risk of cardiovascular disease, neurological disorders, and other health conditions. By measuring these biomarkers, healthcare providers can identify any imbalances or deficiencies in the methylation cycle that may be contributing to these conditions.

The Methylation Profile Plasma test is particularly useful for patients with chronic health conditions that do not respond to conventional treatments, as it provides a more comprehensive picture of their underlying health status. The results of this test can be used to develop personalized treatment plans that target the underlying cause of these conditions and promote optimal health and well-being. This may include dietary changes, nutritional supplements, lifestyle modifications, and other interventions to improve methylation function and support overall health.


The Methylation Profile Plasma - Doctor's Data Test Kit includes the following:

  • Cystathionine | Cysteine
  • Homocysteine
  • Methionine
  • S-adenosylhomocysteine | S-adenosylmethionine | SAM, SAH ratio


Benefits of the Methylation Profile Plasma - Doctor's Data Test Kit:

  1. Assessment of Methylation Status: The test helps evaluate the methylation status of key markers such as homocysteine, cysteine, SAM (S-adenosylmethionine), SAH (S-adenosylhomocysteine), and the SAM/SAH ratio. Methylation plays a vital role in processes like DNA synthesis and repair, neurotransmitter synthesis, detoxification, hormone regulation, and more.
  2. Identification of Methylation Imbalances: Abnormalities in methylation can lead to various health issues such as cardiovascular diseases, neurological disorders, mood disorders, and impaired detoxification. By identifying methylation imbalances, healthcare providers can devise targeted interventions to address these issues.
  3. Personalized Treatment Plans: Based on the test results, healthcare providers can develop personalized treatment plans that may include dietary changes, lifestyle modifications, supplementation with specific vitamins and nutrients (e.g., B vitamins, folate, betaine), and other interventions aimed at optimizing methylation pathways.
  4. Optimization of Health and Wellness: By addressing methylation imbalances, individuals may experience improvements in overall health and wellness. Optimizing methylation pathways can potentially enhance energy levels, cognitive function, mood stability, cardiovascular health, and immune function.
  5. Monitoring Treatment Progress: For individuals undergoing treatment or interventions aimed at improving methylation status, regular monitoring through follow-up testing can help track progress and adjust treatment plans as needed.
  6. Preventive Health Screening: Methylation imbalances can be associated with increased risk for certain chronic diseases. By identifying and addressing these imbalances early on, individuals may lower their risk and potentially prevent the development of associated health conditions.

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