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Essential Estrogens - Hormone Test 24-Hour, Urine - Genova Test Kit

Essential Estrogens - Hormone Test is a targeted urinary hormone test designed to evaluate estrogen metabolism specifically.

Test Code: GD4210

Also Known As:


Specimen Type: Urine


No fasting required. Ship to lab Monday-Thursday only and within 48 hours after collection. Please read all of the directions and the collection procedures prior to starting test. Avoid eating (whole or ground) flax seeds and sesame seeds for at least 48 hours before urine collection begins. Avoid over hydration. Certain medicines may impact test results (e.g. cephalosporins, cimetidine, fibrates and trimethoprim-sulfamethoxazole). Check with physician before stopping medications. Delay collection if you have a urinary tract infection until after completing treatment. If the goal is to evaluate ovulatory function, collect urine between days 19-25 of the menstrual cycle.

Test Results:

21 days once the lab receives the specimen. May take longer based on weather, holiday or lab delays.


You will receive an activation card with the test kit. To activate your test kit, scan the barcode or go to and follow the prompts.  


This test should NOT be performed on individuals with kidney disorders. Abnormal kidney function or use of diuretics may influence test results. Synthetic hormones will not show up on the test and conjugated equine estrogens will show up mostly as estrone.

The 24-Hour Collection captures all urine over a 24-hour time period. It provides a time-average for hormone spikes that may occur throughout a complete circadian rhythm (24 hours). As a result, the 24-Hour provides the highest level of sensitivity to assess very low levels of hormones by providing a direct measurement of the Total Output of each hormone.

This hormone test offers clinical insight into parent estrogens, key estrogen metabolites, and relevant ratios and is useful for initial estrogen assessment as well as follow-up testing to monitor response to therapies and/or to check levels of previously abnormal results.

Estrogen imbalance can produce challenging symptoms during the transitional periods of perimenopause/ menopause and andropause (male menopause) including:

  • Weight gain
  • Anxiety
  • Fatigue
  • Low sex drive and performance issues
  • Hair loss
  • Sleep disturbances
  • Mood instability
  • Brain fog
  • Hot flashes

Why use the Essential Estrogens profile?

In conventional hormone testing, basic parent hormones (estrogens, progesterone, etc.) are usually measured in blood. However, urinary hormone testing, as offered in Essential Estrogens, provides several advantages:

  • Urinary hormone testing provides a more comprehensive look at hormone metabolism, measuring basic parent hormones, as well as compounds produced from parent hormones
  • Emerging research reinforces the potential relationship of disease risk with downstream estrogen metabolites, which are not routinely measured in blood testing and not available in salivary testing

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