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Rhythm Plus, Saliva - Genova Test Kit

The Rhythm Plus hormone test is a comprehensive assessment of estradiol, progesterone, and testosterone spanning a full 28 days.


Test Code: GD4102

Also Known As:

Methodology:

Specimen Type: Saliva

Preparation: No fasting required. Ship to lab Monday-Thursday only. Please read all of the directions and the collection procedures prior to starting test. Transdermal (cream) and sublingual bio-identical hormones may produce artificially high levels in the saliva that do not correlate with blood levels. This increase from cream hormones may last for weeks to months after discontinuing use. The following drugs, herbs and dietary supplements may influence levels of hormones reported in this test: ketoconazole, cimetidine (Tagamet), anastrozole (Arimidex), letrozole (Femara), exemestane (Aromasin), Chrysin, Apigenin, Tribulus terrestris, clomiphene, antiepileptics, digoxin, oral steroids (e.g. Prednisone), cortisone cream, and any steroid-based nasal sprays, inhalers, or eye drops. Check with physician before stopping medications.

Test Results: 7-10 days once the lab receives the specimen. May take longer based on weather, holiday or lab delays.

Description

The Rhythm Plus includes the Adrenocortex Stress Profile and the Comprehensive Melatonin Profile to reveal how the sex hormones are influenced by cortisol, DHEA, and melatonin. Hormone imbalances revealed in this hormone test can help illuminate root causes of disorders such as premenstrual syndrome (PMS), infertility, and menstrual irregularities.

Hormonal balance is the key. Research has long shown that fluctuating levels of estradiol, progesterone, and testosterone play a major role in a woman´s overall health.

Hormone imbalances can affect:

  • Menstrual cycle
  • Mood swings
  • Sleep patterns
  • Appetite level
  • Sex drive

Chronic hormonal imbalances are implicated in disorders such as:

  • PMS
  • Anovulation
  • Infertility
  • Amenorrhea
  • Endometriosis
  • Polycystic Ovary Disease
  • Osteoporosis

Saliva hormone testing provides a thorough analysis of estradiol and progesterone over a full 28-day cycle. Testosterone is measured once from the 28th-day specimen. By utilizing 11 saliva samples for analysis, the relationship and balance of these essential hormones are analyzed more precisely through time. The levels of estradiol and progesterone, as well as the ratio between the two, are clearly graphed for easy reference and patient education.

Unlike serum measurements that typically reflect both bound and unbound fractions of hormones, salivary samples represent only the free (unbound) bioavailable fraction of hormone. Factors that affect binding globulin such as obesity and thyroid function do not influence test results with false high or low test levels.

Rhythm Plus is a hormonal test indicated for both premenopausal and perimenopausal women not currently supplementing with hormones. An analysis of estrogen, progesterone, and testosterone can reveal ovulatory function and trends in hormone production. Hormonal imbalances such as unopposed estrogen, high follicular progesterone, anovulation and luteal phase defects are easily identified. This hormone test is especially useful in the treatment of patients with chronic gynecologic disorders. Additionally, Rhythm Plus includes a circadian analysis of cortisol, melatonin, and an assay of DHEA.

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