Quick Facts
- Sample: Blood draw (serum)
- Fasting: Not required
- Turn-around: 2-3 business days. May take longer based on weather, holiday, or lab delays.
Benefits
- Verify immunity - Confirm hepatitis B protection from vaccination or past infection
- No doctor visit needed - Order online with confidential results delivered securely
- Quick results - Get immunity status within 2-3 business days
- Workplace ready - Obtain documentation for healthcare employment requirements
- Travel preparation - Ensure protection before visiting high-risk areas
- Peace of mind - Know your immunity status for proactive health management
Who Is This Test For?
- Healthcare workers requiring immunity verification for employment
- Travelers planning visits to areas with high hepatitis B rates
- Individuals who completed hepatitis B vaccine series wanting confirmation
- People with potential exposure to hepatitis B virus
- Those with weakened immune systems needing immunity assessment
- Pregnant women checking immunity status before delivery
- Anyone unsure of their hepatitis B protection level
How It Works – Just 3 Steps
- Order online - Select your test and complete checkout without doctor referral
- Visit lab - Get blood drawn at any convenient laboratory location
- Get results - Receive secure, physician-reviewed results within 2-3 days
FAQ
What does this test measure? It measures the concentration of hepatitis B surface antibodies (anti-HBs) in your blood to determine immunity status.
Do I need to fast before this test? No fasting is required. Avoid biotin supplements for 24 hours before testing as they may interfere with results.
What if my results show I'm not immune? Consult your healthcare provider about revaccination or additional protective measures.
How accurate is this test? The test demonstrates high sensitivity and specificity for immunity assessment using immunoassay technology.
Can I use this for work requirements? Yes, results are suitable for workplace documentation, travel requirements, or personal health records.
When should I retest? High-risk individuals may need periodic retesting, typically annually or as recommended by healthcare providers.
More Details
What is the purpose of this test?
The Hepatitis B Surface Antibody Quantitative test measures antibodies against hepatitis B surface antigen (HBsAg) in your blood. This test determines whether you have developed immunity to hepatitis B, either from vaccination or recovery from previous infection (CDC 2024). The quantitative results, reported in mIU/mL, provide precise immunity levels to guide healthcare decisions.
Who would benefit from this test?
Healthcare workers, dialysis patients, and others at increased risk of exposure benefit most from this test (Mayo Clinic 2024). It's also valuable for individuals verifying vaccine response, those with past hepatitis B infection, and anyone requiring proof of immunity for work or travel. The test is especially important given that approximately 862,000 people in the U.S. are living with chronic hepatitis B infection (CDC 2023).
When should I order Hepatitis B Surface Antibody Blood Test, Quantitative?
Order this test after completing the hepatitis B vaccine series, following known exposure, or as part of routine health checks for high-risk groups. Consider testing if you're starting healthcare employment, planning travel to high-risk areas, or if you're unsure of your immunity status. The hepatitis B vaccine is over 95% effective in preventing infection, making immunity verification valuable (CDC 2024).
How do I interpret the results?
Negative
- What it means: No evidence of TB infection
- Typical action: No treatment needed; continue routine screening if high-risk
Positive
- What it means: TB infection likely present
- Typical action: Further evaluation needed; chest X-ray recommended
Indeterminate
- What it means: Test cannot be interpreted
- Typical action: Repeat testing or alternative methods may be necessary
Anti-HBs levels ≥10-12 mIU/mL are considered protective, with the test demonstrating high sensitivity and specificity for immunity assessment.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
Pre-test preparation
No fasting or special preparation is required for most laboratories. Avoid biotin supplements (vitamin B7) for 24 hours prior to sample collection, as they may interfere with results (Mayo Clinic 2024). The test requires a simple blood draw into a serum or plasma tube.
How often should I get tested?
- Healthcare workers: Annually or as required by employer
- High-risk individuals: Every 1–2 years
- Post-vaccination: 1–2 months after the final vaccine dose
- General population: As needed for employment, travel, or other requirements
Why early detection matters
Early detection and vaccination can prevent up to 90% of perinatal hepatitis B infections, reducing long-term liver disease risk (CDC 2023). Healthcare costs for chronic hepatitis B complications exceed $1 billion annually in the U.S. Knowing your immunity status allows for proactive health management and prevents transmission to others.
Related tests you may consider
Hepatitis B Surface Antigen (HBsAg) Test to detect active infection.
Hepatitis B Core Antibody (anti-HBc) Test to identify past or ongoing infection.
Hepatitis B Panel combines multiple tests for comprehensive assessment of infection and immunity status (Hepatitis B Foundation 2024).
