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Immunoglobulins Blood Test, Quantitative, IgA, IgG, and IgM

An Immunoglobulins Blood Test, Quantitative, IgA, IgG, and IgM is useful in detecting or monitoring of monoclonal gammopathies and immune deficiencies.
Sample Report

Test Code: 001768

Also Known As:

Methodology: Immunologic

Preparation: No special preparation required.

Test Results: 2-3 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 7083

Also Known As:

Methodology: Immunoturbidimetric

Preparation: No special preparation required.

Test Results: 3-5 days. May take longer based on weather, holiday or lab delays.

Description


The gamma globulin band as seen in conventional serum protein electrophoresis consists of 5 immunoglobulins. In normal serum, about 80% is immunoglobulin G (IgG), 15% is immunoglobulin A (IgA), 5% is immunoglobulin M (IgM), 0.2% is immunoglobulin D (IgD), and a trace is immunoglobulin E (IgE).

Elevations of IgG, IgA, and IgM may be due to polyclonal immunoglobulin production. Monoclonal gammopathies of all types may lead to a spike in the gamma globulin zone seen on serum protein electrophoresis. Monoclonal elevations of IgG, IgA, IgD, and IgE characterize multiple myeloma.

Monoclonal elevations of IgM occur in macroglobulinemia. Decreased immunoglobulin levels are found in patients with congenital deficiencies.

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