Parietal Cell Antibody Blood Test, ELISA

What is the purpose of this test?

The Parietal Cell Antibody Blood Test, ELISA, is used to detect antibodies against parietal cells in your stomach. Parietal cells are important because they produce stomach acid, which helps digest food. If your immune system mistakenly attacks these cells, it can lead to a condition called autoimmune gastritis, where the stomach lining becomes inflamed and damaged. This can result in vitamin B12 deficiency and anemia.

During the test, a blood sample is taken from your arm and sent to a lab. The lab uses a method called ELISA to check for the presence of parietal cell antibodies. If these antibodies are found, it suggests that your immune system is attacking your stomach cells, leading to problems like gastritis and anemia. Identifying this early allows doctors to provide treatment to manage the condition and prevent complications like severe vitamin B12 deficiency.

Who should get this test?

The Parietal Cell Antibody Blood Test, also known as ELISA, helps doctors understand if a person's immune system is attacking their own stomach lining. This test can benefit people who have certain symptoms or medical conditions. Here are some people who would benefit from this test:

• People experiencing symptoms like stomach pain, bloating, and nausea
• Individuals with a family history of autoimmune diseases
• Those diagnosed with pernicious anemia
• People with a history of chronic gastritis

When should I order this test?

A Parietal Cell Antibody Blood Test, ELISA, should be ordered when a doctor suspects certain conditions related to the stomach and digestive system. This test may be necessary if a person is experiencing symptoms such as:

• Stomach pain
• Bloating
• Nausea

If you or someone you know has any of these symptoms or risk factors, it's important to consult a healthcare professional for proper evaluation and guidance.