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Prostate-specific Antigen (PSA) Free:Total Ratio Blood Test

The Prostate-specific Antigen (PSA) Free:Total Ratio Blood Test compares Total PSA (the amount that is bound to blood proteins) to Free PSA (floats unbound in the blood).

Sample Report

Test Code: 480947

CPT Code: 84153,84154

Also Known As: Fractionated PSA; Prostate Specific Antigen Free and Total; Free PSA and Total PSA; PSA II

Methodology:

Electrochemiluminescence immunoassay (ECLIA)

Specimen Type: Blood

Preparation:

No fasting required. Stop biotin consumption at least 72 hours prior to the collection.

Test Results:

2-3 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 31348

CPT Code: 84153,84154

Also Known As: Fractionated PSA; Prostate Specific Antigen Free and Total; Free PSA and Total PSA; PSA II

Methodology:

Immunoassay (IA)

Specimen Type: Blood

Preparation:

No fasting required. Stop biotin consumption at least 72 hours prior to the collection.

Test Results:

2-3 days. May take longer based on weather, holiday or lab delays.

Description

The Prostate Specific Antigen (PSA) Free:Total Ratio provides several measurements which help to screen for prostate cancer. PSA is a protein produced by the prostate gland. Elevated PSA levels may indicate a higher likelihood of having prostate cancer. However, not all cases of prostate cancer will cause elevated PSA levels and there are conditions other than cancer which may cause elevated PSA.

Free PSA is the portion of PSA which is not bound to other proteins in the blood. Generally, men with lower levels of Free PSA have a higher likelihood of having Prostate Cancer. Free PSA measurements are useful for people with borderline or moderately increased total PSA levels.

The test is used to help determine the need for:

  • Biopsy of the prostate
  • Detect prostate cancer recurring
  • Monitor treatment for prostate cancer

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