Quick Facts
- Sample: Venous blood draw at a local collection site
- Fasting: 8–12 hours recommended (water is fine)
- Turn-around: 1–8 business days. May take longer based on weather, holiday, or lab delays.
Benefits
- Comprehensive cardiometabolic, inflammatory, thyroid, and hormone assessment in one panel.
- Evaluates cardiovascular risk using advanced markers, including homocysteine and hs-CRP.
- Screens blood sugar regulation with fasting glucose (CMP), fasting insulin, and Hemoglobin A1c.
- Assesses thyroid function with TSH, Free T3, Free T4, and Reverse T3.
- Measures sex and adrenal hormones (estradiol, progesterone, testosterone, DHEA-S, AM cortisol).
- Identifies inflammation and immune signaling activity with hs-CRP and TGF-Beta 1.
- Includes iron status (ferritin) and full blood count (CBC) for anemia screening.
- Order online without a doctor’s visit or insurance authorization required.
- Transparent pricing with secure online results access.
Who Is This Test For?
- Adults seeking a detailed functional health assessment beyond a standard wellness panel.
- Individuals with symptoms of hormonal imbalance, thyroid dysfunction, fatigue, or metabolic concerns.
- Patients monitoring cardiometabolic risk factors such as elevated cholesterol, insulin resistance, or inflammation.
- Those working with integrative or functional providers who require expanded biomarker data.
- Individuals tracking progress during hormone, thyroid, or metabolic treatment plans.
How It Works – Just 3 Steps
- Order online — Purchase the test online and schedule a blood draw at a local lab location.
- Visit the lab — Bring your lab order to a nearby lab location for a blood collection.
- Review your results — Access your secure online report, typically within 1–8 business days, with reference ranges included.
FAQ
What biomarkers does this panel test? This panel includes:
- Complete Blood Count (CBC)
- Comprehensive Metabolic Panel (CMP)
- Lipid Panel
- Hemoglobin A1c
- Fasting Insulin
- Homocysteine
- High-Sensitivity C-Reactive Protein (hs-CRP)
- Ferritin
- TGF-Beta 1
- Estradiol
- Progesterone
- Total Testosterone
- DHEA-S
- Cortisol (AM)
- TSH
- Free T3
- Free T4
- Reverse T3
Together, these markers evaluate blood health, metabolic function, cardiovascular risk, inflammation, thyroid balance, adrenal function, and sex hormone status.
Do I need a doctor's order to purchase? No. Walk-In Lab's direct-access model allows you to order without a physician referral or insurance involvement.
Is fasting required? Yes. An 8–12 hour fast is required for accurate glucose, insulin, and lipid results. Water is permitted. Morning collection is recommended to ensure accurate AM cortisol measurement.
How soon after an illness should I test? Wait until you have recovered from acute infection, recent surgery, or major injury. Acute inflammation can temporarily spike hs-CRP and fibrinogen, skewing your baseline results.
How do I get my results? Results are delivered to your secure Walk-In Lab online account.
Should I share results with my doctor? Yes. While reference ranges are provided, interpretation should consider symptoms, medications, and medical history. A licensed clinician can provide individualized guidance.
More Details
What is the purpose of this test?
The Sievers Blood Test Panel #1 provides an in-depth evaluation of cardiometabolic risk, systemic inflammation, thyroid function, adrenal balance, and sex hormone status. It screens for insulin resistance, prediabetes and diabetes risk (via HbA1c and fasting insulin), cardiovascular risk (lipids, homocysteine, hs-CRP), anemia (CBC, ferritin), thyroid dysfunction (TSH, Free T3, Free T4, Reverse T3), and hormone imbalances affecting energy, mood, metabolism, and reproductive health.
Who would benefit from this test?
Adults experiencing fatigue, weight changes, brain fog, mood shifts, menstrual irregularities, low libido, or metabolic concerns may benefit. It is also appropriate for individuals monitoring thyroid therapy, hormone replacement therapy, cardiometabolic risk, or chronic inflammatory conditions under provider supervision.
When should I order this test?
Consider ordering when establishing a comprehensive health baseline, evaluating unexplained symptoms, beginning a new metabolic or hormone-focused treatment plan, or reassessing progress every 3–6 months under clinical guidance.
How do I interpret the results?
Your report includes laboratory reference ranges for each biomarker. Below is a simplified example for Hemoglobin A1c:
Below 5.7%
- What It Means: Normal blood sugar regulation
- Typical Action: Maintain healthy lifestyle
5.7% – 6.4%
- What It Means: Prediabetes range
- Typical Action: Lifestyle modification; clinician follow-up recommended
6.5% or above
- What It Means: Consistent with diabetes range
- Typical Action: Confirmatory testing and medical management required
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
Pre-test preparation
Fast for 8–12 hours before your draw. Water is permitted. Schedule collection in the morning for accurate cortisol results. Continue medications unless directed otherwise by your healthcare provider. Avoid strenuous exercise and alcohol 24 hours before testing, as these may influence hormone and inflammatory markers.
How often should I get tested?
- Healthy adult, low risk: Annually or as your clinician recommends
- Managing prediabetes or diabetes: Every 3–6 months (per ADA, 2025)
- Active cardiovascular risk management: Every 3–6 months, or per cardiologist guidance
- Monitoring lifestyle changes (diet, exercise, weight loss): Every 3–6 months to track progress
- After a significant clinical event: Per your physician's recommendation
Why early detection matters
Insulin resistance, thyroid dysfunction, chronic inflammation, and hormone imbalance can develop gradually and remain undetected on basic screening labs. Early identification allows for targeted lifestyle, nutritional, or medical interventions before more advanced disease develops. Comprehensive panels like this provide a broader physiologic overview to guide proactive health decisions.
Related tests you may consider
Apolipoprotein B (ApoB) Blood Test — Provides a more precise measure of atherogenic particle number than a standard lipid panel, enhancing cardiovascular risk assessment.
Lipoprotein (a) [Lp(a)] Blood Test — Identifies inherited cardiovascular risk not detected on a traditional lipid panel, particularly useful when family history of heart disease is present.
Thyroid Antibodies Panel (TPO & Thyroglobulin Antibodies) — Evaluates for autoimmune thyroid conditions such as Hashimoto’s thyroiditis, complementing TSH, Free T3, Free T4, and Reverse T3 already included in the panel.
