Quick Facts
- Sample: Blood
- Fasting: No fasting is required. Stop biotin consumption at least 72 hours prior to the collection.
- Turnaround: 1-3 business days. May take longer based on weather, holiday or lab delays.
What This Test Measures
This test measures Thyroid Peroxidase (TPO) antibodies in your blood. TPO antibodies are immune proteins that your body produces when it mistakenly targets the thyroid peroxidase enzyme, an enzyme that plays a key role in thyroid hormone production. This test does not measure thyroid hormones such as TSH, T3, or T4.
Because this is an antibody test, it does not directly measure thyroid function or hormone output. Instead, it identifies immune activity that may be associated with autoimmune thyroid conditions. Elevated TPO antibodies are commonly seen in people with chronic thyroiditis, though some people without thyroid disease also have detectable levels.
Benefits
- Detects TPO antibodies linked to autoimmune thyroid activity.
- Supports evaluation when other thyroid test results are inconsistent.
- Provides insight for pregnant women with autoimmune disorders.
- Convenient blood test with no fasting required.
- Helps healthcare providers assess autoimmune thyroid involvement.
Who Is This Test For?
- Individuals with symptoms that may suggest Hashimoto thyroiditis.
- Individuals with symptoms that may suggest Graves' disease.
- People whose prior thyroid test results were inconsistent.
- Pregnant women with autoimmune disorders wanting to assess baby's thyroid risk.
- Women, since antibody prevalence increases with age.
- Individuals working with a healthcare provider on thyroid-related concerns.
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. What is the purpose of this thyroid test?
This test detects and measures Thyroid Peroxidase (TPO) antibodies in the blood. It may help a healthcare provider evaluate autoimmune activity affecting the thyroid, including in connection with Hashimoto thyroiditis or Graves’ disease. This is an antibody test, not a direct measure of thyroid hormone levels, and it does not diagnose a condition on its own.
2. When might I consider ordering this test?
You may consider this test if you have symptoms your healthcare provider believes could be related to Hashimoto thyroiditis or Graves’ disease, or if prior thyroid test results need further context. It may also be considered for pregnant women with autoimmune disorders to help assess a baby’s risk of thyroid dysfunction.
3. How does this test differ from other thyroid tests?
This test measures TPO antibodies, which reflect immune activity that may target the thyroid gland. It does not measure thyroid hormones such as TSH, T3, or T4 and is not interchangeable with hormone or binding-protein testing.
4. Do I need to fast or prepare before this test?
No fasting is required. Stop biotin consumption at least 72 hours before your blood collection.
5. How quickly will I get results?
Results are typically available in 1–3 business days. Weather, holidays, or laboratory delays may extend this timeframe.
6. How do I interpret the results?
The meaning of your TPO antibody result depends on your symptoms, medical history, and other laboratory findings. TPO antibody levels are often considered alongside other thyroid measurements. An elevated result does not automatically confirm a thyroid condition, and a normal result does not rule one out. This antibody result should not be interpreted as a thyroid hormone level.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
7. What should I do if my result is outside the expected range?
Review your result with a qualified healthcare provider. They can determine whether further evaluation or testing is appropriate based on your health history. Do not stop prescribed medication unless instructed by your healthcare provider.
8. How often should I get tested?
Testing frequency depends on your symptoms and health history. Follow your healthcare provider’s guidance, as there is no standard repeat-testing schedule for this test.
Pre test preparation
No fasting is required. Stop biotin consumption at least 72 hours prior to the collection. Do not stop prescribed medication unless instructed by your healthcare provider.
