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Thyrotropin Receptor Antibody Blood Test

A Thyrotropin Receptor Antibody Blood Test is used in the diagnosis of hyperthyroidism and Graves' disease.
Sample Report

Test Code: 010314

Also Known As: TRab, TSH Receptor Antibody

Methodology:

Preparation: No fasting required. Stop biotin consumption at least 72 hours prior to the collection.

Test Results: 3-4 days. May take longer based on weather, holiday or lab delays.


Test Code: 38683

Also Known As: TRab, TSH Receptor Antibody

Methodology: Enzyme Linked Immunosorbent Assay (ELISA)

Preparation: No special preparation required.

Test Results: 5-7 days. May take longer based on weather, holiday or lab delays.

Description

Thyrotropin-receptor antibody is an autoantibody to the thyroid cell receptor for thyroid-stimulating hormone. It can be demonstrated in 90% of patients with Graves' disease, and is the cause of the hyperthyroidism of that condition. The characterization of TRA resolved much confusion about long-acting thyroid stimulator (LATS) and LATS protector, which are both, in fact, thyroid-stimulating autoantibodies which simply behaved differently in animal test systems. These antibodies are present in 50% of euthyroid Graves' disease as well as hyperthyroid patients. They play a major role in the pathogenesis of Graves' disease. Detection of these antibodies is useful in prediction of neonatal hyperthyroidism and prediction of relapse of hyperthyroidism.

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